Name | Number of supported studies | Average coverage | |
---|---|---|---|
ON-bipolar cell | 3 studies | 49% ± 20% |
Insufficient scRNA-seq data for expression of GABRR2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 68.88 | 89 / 89 | 34% | 0.78 | 310 / 901 |
lung | 100% | 105.47 | 576 / 578 | 25% | 0.44 | 291 / 1155 |
esophagus | 90% | 52.17 | 1303 / 1445 | 30% | 0.51 | 54 / 183 |
thymus | 100% | 70.01 | 650 / 653 | 16% | 0.30 | 98 / 605 |
uterus | 99% | 75.39 | 168 / 170 | 16% | 0.29 | 72 / 459 |
intestine | 99% | 79.32 | 959 / 966 | 9% | 0.16 | 49 / 527 |
ovary | 97% | 44.55 | 175 / 180 | 10% | 0.20 | 44 / 430 |
adrenal gland | 100% | 47.06 | 258 / 258 | 5% | 0.09 | 12 / 230 |
bladder | 95% | 67.57 | 20 / 21 | 9% | 0.17 | 43 / 504 |
breast | 96% | 42.25 | 442 / 459 | 7% | 0.12 | 77 / 1118 |
prostate | 98% | 60.60 | 241 / 245 | 4% | 0.06 | 22 / 502 |
spleen | 100% | 158.80 | 241 / 241 | 0% | 0 | 0 / 0 |
stomach | 90% | 39.77 | 322 / 359 | 10% | 0.18 | 29 / 286 |
blood vessel | 97% | 59.70 | 1291 / 1335 | 0% | 0 | 0 / 0 |
heart | 95% | 47.76 | 818 / 861 | 0% | 0 | 0 / 0 |
muscle | 95% | 58.13 | 759 / 803 | 0% | 0 | 0 / 0 |
adipose | 94% | 50.28 | 1133 / 1204 | 0% | 0 | 0 / 0 |
pancreas | 79% | 22.95 | 260 / 328 | 13% | 0.20 | 24 / 178 |
peripheral blood | 86% | 79.57 | 801 / 929 | 0% | 0 | 0 / 0 |
liver | 76% | 27.19 | 172 / 226 | 2% | 0.03 | 8 / 406 |
skin | 55% | 10.87 | 990 / 1809 | 10% | 0.17 | 45 / 472 |
brain | 34% | 7.59 | 906 / 2642 | 19% | 0.33 | 131 / 705 |
lymph node | 0% | 0 | 0 / 0 | 34% | 0.55 | 10 / 29 |
eye | 0% | 0 | 0 / 0 | 5% | 0.30 | 4 / 80 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007601 | Biological process | visual perception |
GO_0042391 | Biological process | regulation of membrane potential |
GO_0007165 | Biological process | signal transduction |
GO_1902476 | Biological process | chloride transmembrane transport |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0060078 | Biological process | regulation of postsynaptic membrane potential |
GO_0007214 | Biological process | gamma-aminobutyric acid signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_1902495 | Cellular component | transmembrane transporter complex |
GO_0043005 | Cellular component | neuron projection |
GO_0098982 | Cellular component | GABA-ergic synapse |
GO_0034707 | Cellular component | chloride channel complex |
GO_0045202 | Cellular component | synapse |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_1902711 | Cellular component | GABA-A receptor complex |
GO_0019904 | Molecular function | protein domain specific binding |
GO_1904315 | Molecular function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
GO_0004890 | Molecular function | GABA-A receptor activity |
GO_0030594 | Molecular function | neurotransmitter receptor activity |
GO_0022851 | Molecular function | GABA-gated chloride ion channel activity |
GO_0005254 | Molecular function | chloride channel activity |
Gene name | GABRR2 |
Protein name | Gamma-aminobutyric acid receptor subunit rho-2 (GABA(A) receptor subunit rho-2) (GABA(C) receptor) |
Synonyms | |
Description | FUNCTION: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission. |
Accessions | ENST00000402938.4 [P28476-1] P28476 |