GABRR2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GABRR2 at tissue level.

III. Associated gene sets

GO_0007601Biological processvisual perception
GO_0042391Biological processregulation of membrane potential
GO_0007165Biological processsignal transduction
GO_1902476Biological processchloride transmembrane transport
GO_0007268Biological processchemical synaptic transmission
GO_0060078Biological processregulation of postsynaptic membrane potential
GO_0007214Biological processgamma-aminobutyric acid signaling pathway
GO_0005886Cellular componentplasma membrane
GO_1902495Cellular componenttransmembrane transporter complex
GO_0043005Cellular componentneuron projection
GO_0098982Cellular componentGABA-ergic synapse
GO_0034707Cellular componentchloride channel complex
GO_0045202Cellular componentsynapse
GO_0045211Cellular componentpostsynaptic membrane
GO_1902711Cellular componentGABA-A receptor complex
GO_0019904Molecular functionprotein domain specific binding
GO_1904315Molecular functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
GO_0004890Molecular functionGABA-A receptor activity
GO_0030594Molecular functionneurotransmitter receptor activity
GO_0022851Molecular functionGABA-gated chloride ion channel activity
GO_0005254Molecular functionchloride channel activity

IV. Literature review

[source]
Gene nameGABRR2
Protein nameGamma-aminobutyric acid receptor subunit rho-2 (GABA(A) receptor subunit rho-2) (GABA(C) receptor)
Synonyms
DescriptionFUNCTION: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission.

AccessionsENST00000402938.4 [P28476-1]
P28476