GABRA6 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GABRA6 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GABRA6 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_1904862Biological processinhibitory synapse assembly
GO_1902476Biological processchloride transmembrane transport
GO_0060078Biological processregulation of postsynaptic membrane potential
GO_0051932Biological processsynaptic transmission, GABAergic
GO_0007214Biological processgamma-aminobutyric acid signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0099192Cellular componentcerebellar Golgi cell to granule cell synapse
GO_1902495Cellular componenttransmembrane transporter complex
GO_0098794Cellular componentpostsynapse
GO_0043005Cellular componentneuron projection
GO_0034707Cellular componentchloride channel complex
GO_0045202Cellular componentsynapse
GO_1902711Cellular componentGABA-A receptor complex
GO_0099634Cellular componentpostsynaptic specialization membrane
GO_0032590Cellular componentdendrite membrane
GO_1904315Molecular functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
GO_0004890Molecular functionGABA-A receptor activity
GO_0005254Molecular functionchloride channel activity
GO_0022851Molecular functionGABA-gated chloride ion channel activity
GO_0008503Molecular functionbenzodiazepine receptor activity

IV. Literature review

[source]
Gene nameGABRA6
Protein nameGamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6)
Gamma-aminobutyric acid type A receptor subunit alpha6
Synonyms
DescriptionFUNCTION: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

AccessionsENST00000274545.10
ENST00000523691.1
H0YBS7
ENST00000520000.5
ENST00000523217.5
H0YBP3
E7EV53
ENST00000517823.5
H0YAS3
Q16445