Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 7 studies | 39% ± 23% | |
| oligodendrocyte precursor cell | 6 studies | 25% ± 9% | |
| GABAergic neuron | 5 studies | 34% ± 16% | |
| interneuron | 4 studies | 34% ± 17% | |
| neuron | 3 studies | 20% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 34% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 93% | 1124.31 | 2467 / 2642 | 87% | 25.69 | 615 / 705 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.09 | 1 / 1 |
| bladder | 24% | 32.86 | 5 / 21 | 49% | 4.61 | 245 / 504 |
| esophagus | 11% | 13.53 | 155 / 1445 | 52% | 4.56 | 95 / 183 |
| skin | 1% | 1.68 | 25 / 1809 | 52% | 6.70 | 246 / 472 |
| lung | 0% | 0.25 | 1 / 578 | 48% | 4.76 | 555 / 1155 |
| uterus | 2% | 3.60 | 4 / 170 | 40% | 3.75 | 183 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 31% | 1.71 | 14 / 45 |
| ovary | 0% | 0 | 0 / 180 | 31% | 2.13 | 133 / 430 |
| stomach | 0% | 0 | 0 / 359 | 18% | 2.76 | 51 / 286 |
| intestine | 0% | 0.18 | 2 / 966 | 13% | 1.08 | 66 / 527 |
| liver | 0% | 0 | 0 / 226 | 12% | 0.67 | 47 / 406 |
| pancreas | 0% | 0 | 0 / 328 | 10% | 0.60 | 18 / 178 |
| breast | 0% | 0 | 0 / 459 | 9% | 0.87 | 103 / 1118 |
| adrenal gland | 0% | 0 | 0 / 258 | 5% | 0.48 | 12 / 230 |
| prostate | 2% | 2.42 | 5 / 245 | 1% | 0.03 | 4 / 502 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.19 | 2 / 80 |
| thymus | 0% | 0 | 0 / 653 | 2% | 0.10 | 12 / 605 |
| kidney | 0% | 0 | 0 / 89 | 1% | 0.27 | 12 / 901 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_1904862 | Biological process | inhibitory synapse assembly |
| GO_1902476 | Biological process | chloride transmembrane transport |
| GO_0060078 | Biological process | regulation of postsynaptic membrane potential |
| GO_0051932 | Biological process | synaptic transmission, GABAergic |
| GO_0007214 | Biological process | gamma-aminobutyric acid signaling pathway |
| GO_0005886 | Cellular component | plasma membrane |
| GO_1902495 | Cellular component | transmembrane transporter complex |
| GO_0098794 | Cellular component | postsynapse |
| GO_0043005 | Cellular component | neuron projection |
| GO_0034707 | Cellular component | chloride channel complex |
| GO_0045202 | Cellular component | synapse |
| GO_0045211 | Cellular component | postsynaptic membrane |
| GO_1902711 | Cellular component | GABA-A receptor complex |
| GO_0032590 | Cellular component | dendrite membrane |
| GO_0004890 | Molecular function | GABA-A receptor activity |
| GO_0005254 | Molecular function | chloride channel activity |
| GO_0022851 | Molecular function | GABA-gated chloride ion channel activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008503 | Molecular function | benzodiazepine receptor activity |
| Gene name | GABRA3 |
| Protein name | Gamma-aminobutyric acid receptor subunit alpha-3 (GABA(A) receptor subunit alpha-3) |
| Synonyms | |
| Description | FUNCTION: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. . |
| Accessions | ENST00000370314.9 ENST00000535043.1 P34903 |