FXR2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of FXR2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3136.14	1445 / 1445	100%	26.65	183 / 183
brain	100%	4380.64	2641 / 2642	100%	54.24	705 / 705
skin	100%	2721.85	1808 / 1809	100%	44.00	472 / 472
prostate	100%	3128.00	245 / 245	100%	34.61	501 / 502
ovary	100%	2588.31	180 / 180	100%	22.47	429 / 430
thymus	100%	2558.77	652 / 653	100%	35.32	604 / 605
lung	100%	2690.22	577 / 578	100%	27.51	1152 / 1155
uterus	100%	3078.82	170 / 170	100%	31.11	457 / 459
intestine	100%	2926.54	966 / 966	99%	21.75	524 / 527
breast	100%	2436.73	459 / 459	99%	32.68	1110 / 1118
bladder	100%	3102.48	21 / 21	99%	27.15	498 / 504
kidney	100%	2704.53	89 / 89	99%	26.56	890 / 901
adrenal gland	100%	3665.57	258 / 258	99%	39.61	227 / 230
stomach	100%	2196.22	359 / 359	99%	20.95	282 / 286
liver	100%	1569.08	225 / 226	98%	17.93	397 / 406
pancreas	98%	1180.72	321 / 328	99%	24.93	177 / 178
adipose	100%	2479.87	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	38.43	80 / 80
lymph node	0%	0	0 / 0	100%	25.96	29 / 29
muscle	100%	8984.92	803 / 803	0%	0	0 / 0
spleen	100%	2362.90	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	33.00	45 / 45
ureter	0%	0	0 / 0	100%	10.67	1 / 1
blood vessel	100%	3096.39	1334 / 1335	0%	0	0 / 0
heart	99%	5277.74	850 / 861	0%	0	0 / 0
peripheral blood	90%	1438.15	838 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0099577	Biological process	regulation of translation at presynapse, modulating synaptic transmission
GO_0048170	Biological process	positive regulation of long-term neuronal synaptic plasticity
GO_0043488	Biological process	regulation of mRNA stability
GO_0051028	Biological process	mRNA transport
GO_0021542	Biological process	dentate gyrus development
GO_0061157	Biological process	mRNA destabilization
GO_0048513	Biological process	animal organ development
GO_0045727	Biological process	positive regulation of translation
GO_0098793	Cellular component	presynapse
GO_0016020	Cellular component	membrane
GO_0098794	Cellular component	postsynapse
GO_0043005	Cellular component	neuron projection
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0010494	Cellular component	cytoplasmic stress granule
GO_0005634	Cellular component	nucleus
GO_0042803	Molecular function	protein homodimerization activity
GO_0045182	Molecular function	translation regulator activity
GO_0042802	Molecular function	identical protein binding
GO_0003723	Molecular function	RNA binding
GO_0046982	Molecular function	protein heterodimerization activity
GO_0003730	Molecular function	mRNA 3'-UTR binding
GO_0005515	Molecular function	protein binding

Gene name	FXR2
Protein name	Alternative protein FXR2 FMR1 autosomal homolog 2 RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Synonyms	FMR1L2
Description	FUNCTION: mRNA-binding protein that acts as a regulator of mRNAs translation and/or stability, and which is required for adult hippocampal neurogenesis (By similarity). Specifically binds to AU-rich elements (AREs) in the 3'-UTR of target mRNAs (By similarity). Promotes formation of some phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to AREs-containing mRNAs: mRNAs storage into membraneless compartments regulates their translation and/or stability (By similarity). Acts as a regulator of adult hippocampal neurogenesis by regulating translation and/or stability of NOG mRNA, thereby preventing NOG protein expression in the dentate gyrus (By similarity). .
Accessions	ENST00000704984.1 ENST00000250113.12 P51116 L0R4Y0 A0A994J7P9 ENST00000571597.1 I3L1Z2

FXR2 report