FTSJ3 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	4 studies	26% ± 8%	Explore
dendritic cell	3 studies	19% ± 2%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of FTSJ3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3399.41	1445 / 1445	100%	38.02	183 / 183
ovary	100%	3892.82	180 / 180	100%	27.78	430 / 430
prostate	100%	3666.51	245 / 245	100%	47.16	502 / 502
uterus	100%	3892.90	170 / 170	100%	54.35	458 / 459
liver	100%	1864.04	226 / 226	100%	32.37	405 / 406
thymus	100%	3478.30	653 / 653	100%	38.21	603 / 605
lung	100%	2830.72	577 / 578	100%	43.89	1153 / 1155
breast	100%	3417.12	459 / 459	100%	52.74	1114 / 1118
intestine	100%	3517.89	966 / 966	100%	37.68	525 / 527
skin	100%	4366.73	1809 / 1809	100%	59.78	470 / 472
pancreas	99%	1642.34	326 / 328	100%	38.76	178 / 178
stomach	100%	2618.48	359 / 359	99%	33.17	284 / 286
bladder	100%	3609.62	21 / 21	99%	47.15	498 / 504
brain	99%	1597.90	2609 / 2642	100%	44.24	705 / 705
kidney	100%	3082.82	89 / 89	98%	33.87	883 / 901
adrenal gland	100%	3597.45	258 / 258	91%	19.79	210 / 230
adipose	100%	3556.78	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3053.12	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	43.92	80 / 80
lymph node	0%	0	0 / 0	100%	61.33	29 / 29
spleen	100%	3912.37	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	52.92	45 / 45
ureter	0%	0	0 / 0	100%	21.61	1 / 1
muscle	100%	2911.26	802 / 803	0%	0	0 / 0
heart	98%	2430.45	847 / 861	0%	0	0 / 0
peripheral blood	93%	2179.82	868 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0000463	Biological process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0001510	Biological process	RNA methylation
GO_0000466	Biological process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0031167	Biological process	rRNA methylation
GO_0030687	Cellular component	preribosome, large subunit precursor
GO_0005730	Cellular component	nucleolus
GO_0005694	Cellular component	chromosome
GO_0005654	Cellular component	nucleoplasm
GO_0030688	Cellular component	preribosome, small subunit precursor
GO_0008650	Molecular function	rRNA (uridine-2'-O-)-methyltransferase activity
GO_0016435	Molecular function	rRNA (guanine) methyltransferase activity
GO_0005515	Molecular function	protein binding
GO_0062105	Molecular function	RNA 2'-O-methyltransferase activity
GO_0003723	Molecular function	RNA binding

Gene name	FTSJ3
Protein name	pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3) FtsJ RNA 2'-O-methyltransferase 3
Synonyms	SB92
Description	FUNCTION: RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. .; FUNCTION: (Microbial infection) In case of infection by HIV-1 virus, recruited to HIV-1 RNA and catalyzes 2'-O-methylation of the viral genome, allowing HIV-1 virus to escape the innate immune system . RNA 2'-O-methylation provides a molecular signature for discrimination of self from non-self and is used by HIV-1 to evade innate immune recognition by IFIH1/MDA5 . Mediates methylation of internal residues of HIV-1 RNA, with a strong preference for adenosine . Recruited to HIV-1 RNA via interaction with TARBP2/TRBP . .
Accessions	J3QKT6 ENST00000579831.1 J3QR05 ENST00000580272.5 Q8IY81 ENST00000427159.7 J3KRY4 J3KS74 ENST00000581209.5 J3KS36 ENST00000579569.5 ENST00000585145.1 ENST00000584574.5 J3QSE2 ENST00000584193.5 J3QRS5

FTSJ3 report