FRS3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FRS3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FRS3 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0008543Biological processfibroblast growth factor receptor signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005104Molecular functionfibroblast growth factor receptor binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0005068Molecular functiontransmembrane receptor protein tyrosine kinase adaptor activity

IV. Literature review

[source]
Gene nameFRS3
Protein nameFibroblast growth factor receptor substrate 3 (Testicular tissue protein Li 71)
Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FGFR-signaling adaptor SNT2) (Suc1-associated neurotrophic factor target 2) (SNT-2)
Fibroblast growth factor receptor substrate 3
SynonymshCG_1779355
DescriptionFUNCTION: Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. .

AccessionsO43559
ENST00000259748.6
ENST00000426290.1
ENST00000422888.5
A0A0A0MSM8
A6PVU0
A0A140VJJ7
ENST00000373018.7