FRAT1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FRAT1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FRAT1 at tissue level.

III. Associated gene sets

GO_0046825Biological processregulation of protein export from nucleus
GO_0090263Biological processpositive regulation of canonical Wnt signaling pathway
GO_0060070Biological processcanonical Wnt signaling pathway
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0140678Molecular functionmolecular function inhibitor activity

IV. Literature review

[source]
Gene nameFRAT1
Protein nameProto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas 1) (FRAT-1)
Synonyms
DescriptionFUNCTION: Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. .

AccessionsENST00000371021.5
Q92837