I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| classical monocyte | 8 studies | 24% ± 6% | |
| monocyte | 3 studies | 18% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 8 studies | 24% ± 6% | |
| monocyte | 3 studies | 18% ± 3% |
Insufficient scRNA-seq data for expression of FOLR3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 198.96 | 89 / 89 | 20% | 2.00 | 183 / 901 |
| lung | 97% | 242.68 | 560 / 578 | 23% | 1.25 | 264 / 1155 |
| spleen | 100% | 1198.83 | 241 / 241 | 0% | 0 | 0 / 0 |
| thymus | 73% | 33.60 | 478 / 653 | 19% | 0.50 | 113 / 605 |
| ovary | 6% | 1.45 | 11 / 180 | 85% | 15.21 | 365 / 430 |
| peripheral blood | 81% | 7173.69 | 755 / 929 | 0% | 0 | 0 / 0 |
| adipose | 56% | 44.67 | 679 / 1204 | 0% | 0 | 0 / 0 |
| skin | 43% | 14.19 | 783 / 1809 | 2% | 0.04 | 9 / 472 |
| liver | 38% | 16.92 | 86 / 226 | 2% | 0.06 | 10 / 406 |
| esophagus | 16% | 6.03 | 235 / 1445 | 20% | 1.44 | 36 / 183 |
| stomach | 23% | 14.33 | 82 / 359 | 10% | 0.28 | 28 / 286 |
| adrenal gland | 29% | 13.10 | 74 / 258 | 4% | 0.10 | 9 / 230 |
| breast | 28% | 7.84 | 128 / 459 | 2% | 0.11 | 27 / 1118 |
| uterus | 12% | 5.87 | 20 / 170 | 18% | 2.96 | 84 / 459 |
| bladder | 19% | 13.14 | 4 / 21 | 11% | 0.58 | 54 / 504 |
| heart | 28% | 9.95 | 239 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 9% | 3.03 | 31 / 328 | 16% | 0.29 | 28 / 178 |
| intestine | 16% | 6.58 | 153 / 966 | 5% | 0.14 | 26 / 527 |
| tonsil | 0% | 0 | 0 / 0 | 18% | 0.86 | 8 / 45 |
| blood vessel | 18% | 9.28 | 236 / 1335 | 0% | 0 | 0 / 0 |
| brain | 6% | 1.67 | 170 / 2642 | 10% | 0.22 | 67 / 705 |
| prostate | 14% | 7.35 | 35 / 245 | 1% | 0.01 | 4 / 502 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.34 | 3 / 29 |
| muscle | 7% | 1.66 | 54 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007155 | Biological process | cell adhesion |
| GO_0035036 | Biological process | sperm-egg recognition |
| GO_0007342 | Biological process | fusion of sperm to egg plasma membrane involved in single fertilization |
| GO_0015884 | Biological process | folic acid transport |
| GO_1904724 | Cellular component | tertiary granule lumen |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0005576 | Cellular component | extracellular region |
| GO_0035580 | Cellular component | specific granule lumen |
| GO_0019898 | Cellular component | extrinsic component of membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005542 | Molecular function | folic acid binding |
| GO_0038023 | Molecular function | signaling receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | FOLR3 |
| Protein name | Folate receptor gamma (FR-gamma) (Folate receptor 3) Folate receptor gamma |
| Synonyms | |
| Description | FUNCTION: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate. |
| Accessions | ENST00000612844.4 [P41439-4] ENST00000622388.4 ENST00000611028.3 [P41439-1] A0A087WYI3 ENST00000546166.1 F5H2G8 P41439 |
