FIGNL1 | OmnibusX

Name	Number of supported studies	Average coverage
GABAergic neuron	3 studies	17% ± 1%	Explore
glutamatergic neuron	3 studies	25% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of FIGNL1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	99%	611.14	1436 / 1445	100%	17.29	183 / 183
brain	99%	542.72	2622 / 2642	99%	10.78	699 / 705
breast	99%	536.63	456 / 459	99%	13.31	1103 / 1118
uterus	100%	813.99	170 / 170	98%	17.60	449 / 459
ovary	100%	968.91	180 / 180	97%	8.89	417 / 430
intestine	100%	522.49	964 / 966	97%	12.51	512 / 527
bladder	100%	456.81	21 / 21	96%	11.98	482 / 504
skin	100%	831.30	1806 / 1809	95%	12.70	449 / 472
stomach	95%	329.70	341 / 359	97%	12.84	278 / 286
lung	91%	383.04	525 / 578	98%	15.04	1137 / 1155
prostate	100%	535.26	245 / 245	88%	5.49	442 / 502
thymus	99%	448.00	647 / 653	88%	6.51	531 / 605
adrenal gland	99%	468.25	256 / 258	87%	6.73	201 / 230
pancreas	91%	220.60	300 / 328	88%	5.54	157 / 178
kidney	96%	301.76	85 / 89	80%	5.36	720 / 901
liver	95%	266.94	214 / 226	59%	3.95	240 / 406
spleen	100%	741.62	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	23.82	45 / 45
adipose	99%	419.38	1194 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	14.00	28 / 29
muscle	95%	300.71	763 / 803	0%	0	0 / 0
blood vessel	92%	241.84	1233 / 1335	0%	0	0 / 0
heart	89%	224.43	768 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	54%	2.87	43 / 80
peripheral blood	34%	558.81	320 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0010569	Biological process	regulation of double-strand break repair via homologous recombination
GO_0033687	Biological process	osteoblast proliferation
GO_0001649	Biological process	osteoblast differentiation
GO_0046034	Biological process	ATP metabolic process
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0000226	Biological process	microtubule cytoskeleton organization
GO_2001243	Biological process	negative regulation of intrinsic apoptotic signaling pathway
GO_0071479	Biological process	cellular response to ionizing radiation
GO_0007140	Biological process	male meiotic nuclear division
GO_0051726	Biological process	regulation of cell cycle
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0000228	Cellular component	nuclear chromosome
GO_0070062	Cellular component	extracellular exosome
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0016787	Molecular function	hydrolase activity
GO_0000287	Molecular function	magnesium ion binding
GO_0008568	Molecular function	microtubule severing ATPase activity
GO_0005524	Molecular function	ATP binding
GO_0005515	Molecular function	protein binding
GO_0016887	Molecular function	ATP hydrolysis activity

Gene name	FIGNL1
Protein name	Fidgetin-like protein 1 (EC 3.6.4.-) Fidgetin like 1
Synonyms
Description	FUNCTION: Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation . May play a role in the control of male meiosis dynamic (By similarity). .
Accessions	C9JKI6 Q6PIW4 ENST00000419119.1 [Q6PIW4-1] C9JTB2 C9JSC4 ENST00000615084.4 [Q6PIW4-1] ENST00000356889.8 [Q6PIW4-1] C9JHJ4 ENST00000440350.5 ENST00000395556.6 [Q6PIW4-1] ENST00000448788.1 ENST00000436590.5 C9JP37 ENST00000433017.6 [Q6PIW4-1] ENST00000422854.5 ENST00000617389.4 [Q6PIW4-1] ENST00000435566.5 ENST00000420829.5 C9JTG6

FIGNL1 report