Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 17 studies | 45% ± 18% | |
oligodendrocyte precursor cell | 14 studies | 50% ± 20% | |
oligodendrocyte | 12 studies | 33% ± 15% | |
adipocyte | 9 studies | 46% ± 15% | |
fibroblast | 9 studies | 29% ± 18% | |
GABAergic neuron | 7 studies | 35% ± 10% | |
pericyte | 7 studies | 27% ± 10% | |
endothelial cell | 5 studies | 29% ± 16% | |
cardiac muscle cell | 5 studies | 34% ± 7% | |
glutamatergic neuron | 5 studies | 41% ± 13% | |
interneuron | 4 studies | 38% ± 17% | |
mesothelial cell | 4 studies | 29% ± 12% | |
smooth muscle cell | 4 studies | 29% ± 7% | |
neuron | 4 studies | 43% ± 15% | |
hepatic stellate cell | 3 studies | 39% ± 11% | |
GABAergic interneuron | 3 studies | 24% ± 3% | |
glial cell | 3 studies | 37% ± 17% | |
OFF-bipolar cell | 3 studies | 31% ± 10% | |
glycinergic amacrine cell | 3 studies | 31% ± 12% | |
hepatocyte | 3 studies | 39% ± 14% | |
ependymal cell | 3 studies | 43% ± 26% | |
Schwann cell | 3 studies | 45% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 2125.82 | 180 / 180 | 83% | 4.78 | 356 / 430 |
kidney | 96% | 693.75 | 85 / 89 | 87% | 4.93 | 780 / 901 |
brain | 84% | 497.10 | 2218 / 2642 | 97% | 7.94 | 684 / 705 |
skin | 85% | 470.24 | 1546 / 1809 | 93% | 5.61 | 441 / 472 |
prostate | 97% | 856.28 | 237 / 245 | 71% | 1.51 | 356 / 502 |
pancreas | 99% | 775.00 | 326 / 328 | 58% | 1.34 | 104 / 178 |
adrenal gland | 98% | 868.60 | 252 / 258 | 59% | 2.51 | 136 / 230 |
liver | 96% | 782.55 | 216 / 226 | 49% | 1.27 | 197 / 406 |
bladder | 100% | 871.10 | 21 / 21 | 43% | 1.29 | 217 / 504 |
breast | 98% | 1020.76 | 451 / 459 | 44% | 1.53 | 492 / 1118 |
lung | 94% | 698.14 | 541 / 578 | 46% | 1.24 | 537 / 1155 |
uterus | 88% | 820.14 | 150 / 170 | 45% | 1.38 | 207 / 459 |
stomach | 97% | 714.56 | 349 / 359 | 25% | 0.95 | 71 / 286 |
thymus | 94% | 586.83 | 615 / 653 | 26% | 0.40 | 160 / 605 |
esophagus | 83% | 1061.45 | 1199 / 1445 | 36% | 1.76 | 66 / 183 |
intestine | 93% | 931.44 | 903 / 966 | 10% | 0.24 | 55 / 527 |
spleen | 100% | 1502.84 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1999.79 | 1331 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 1494.46 | 1198 / 1204 | 0% | 0 | 0 / 0 |
heart | 96% | 1031.07 | 830 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 7.17 | 77 / 80 |
muscle | 49% | 167.55 | 396 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 31% | 0.55 | 14 / 45 |
peripheral blood | 1% | 3.09 | 7 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0051301 | Biological process | cell division |
GO_0000226 | Biological process | microtubule cytoskeleton organization |
GO_0016363 | Cellular component | nuclear matrix |
GO_0005813 | Cellular component | centrosome |
GO_0005874 | Cellular component | microtubule |
GO_0005737 | Cellular component | cytoplasm |
GO_0008568 | Molecular function | microtubule severing ATPase activity |
GO_0005515 | Molecular function | protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | FIGN |
Protein name | Fidgetin Fidgetin, microtubule severing factor |
Synonyms | |
Description | FUNCTION: ATP-dependent microtubule severing protein. Severs microtubules along their length and depolymerizes their ends, primarily the minus-end, that may lead to the suppression of microtubule growth from and attachment to centrosomes. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. . |
Accessions | B8ZZS6 ENST00000409634.5 ENST00000333129.4 Q5HY92 |