FGFBP3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FGFBP3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FGFBP3 at tissue level.

III. Associated gene sets

GO_0045743Biological processpositive regulation of fibroblast growth factor receptor signaling pathway
GO_0007267Biological processcell-cell signaling
GO_0043117Biological processpositive regulation of vascular permeability
GO_0005576Cellular componentextracellular region
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0008201Molecular functionheparin binding
GO_0017134Molecular functionfibroblast growth factor binding
GO_0019838Molecular functiongrowth factor binding

IV. Literature review

[source]
Gene nameFGFBP3
Protein nameFibroblast growth factor-binding protein 3 (FGF-BP3) (FGF-binding protein 3) (FGFBP-3)
SynonymsPSEC0101
C10orf13
DescriptionFUNCTION: Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability. .

AccessionsENST00000311575.6
Q8TAT2