FGD1 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	4 studies	30% ± 12%	Explore
GABAergic neuron	3 studies	29% ± 9%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	23% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	100%	1293.69	1808 / 1809	98%	26.19	464 / 472
brain	100%	1088.99	2639 / 2642	97%	13.46	685 / 705
ovary	100%	1564.13	180 / 180	90%	14.31	388 / 430
breast	100%	874.33	459 / 459	89%	10.54	998 / 1118
uterus	100%	1584.99	170 / 170	83%	11.15	382 / 459
adrenal gland	100%	1074.61	258 / 258	78%	5.50	179 / 230
esophagus	100%	1091.85	1445 / 1445	70%	11.15	128 / 183
prostate	100%	1032.71	245 / 245	69%	4.06	348 / 502
lung	100%	659.37	577 / 578	66%	6.23	767 / 1155
pancreas	99%	389.70	324 / 328	60%	3.43	106 / 178
stomach	100%	654.26	358 / 359	53%	4.68	151 / 286
bladder	100%	1061.86	21 / 21	51%	4.46	255 / 504
thymus	100%	833.40	653 / 653	49%	2.50	297 / 605
kidney	100%	704.11	89 / 89	41%	2.56	367 / 901
intestine	100%	967.20	965 / 966	36%	2.87	189 / 527
adipose	100%	886.92	1204 / 1204	0%	0	0 / 0
blood vessel	100%	1126.15	1335 / 1335	0%	0	0 / 0
spleen	100%	578.33	241 / 241	0%	0	0 / 0
heart	99%	700.18	855 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	99%	15.36	79 / 80
tonsil	0%	0	0 / 0	91%	7.90	41 / 45
liver	38%	83.11	85 / 226	21%	1.20	86 / 406
muscle	51%	116.74	407 / 803	0%	0	0 / 0
peripheral blood	7%	12.23	63 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007165	Biological process	signal transduction
GO_0046847	Biological process	filopodium assembly
GO_0051056	Biological process	regulation of small GTPase mediated signal transduction
GO_0008360	Biological process	regulation of cell shape
GO_0030036	Biological process	actin cytoskeleton organization
GO_0043087	Biological process	regulation of GTPase activity
GO_0007010	Biological process	cytoskeleton organization
GO_0009887	Biological process	animal organ morphogenesis
GO_0001726	Cellular component	ruffle
GO_0005856	Cellular component	cytoskeleton
GO_0005829	Cellular component	cytosol
GO_0030027	Cellular component	lamellipodium
GO_0005794	Cellular component	Golgi apparatus
GO_0005737	Cellular component	cytoplasm
GO_0005085	Molecular function	guanyl-nucleotide exchange factor activity
GO_0031267	Molecular function	small GTPase binding
GO_0046872	Molecular function	metal ion binding

Gene name	FGD1
Protein name	FGD1 FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)
Synonyms	ZFYVE3 FGDY
Description	FUNCTION: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. .
Accessions	P98174 A0A2X0SFE1 ENST00000375135.4

FGD1 report