Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 6 studies | 22% ± 6% | |
ciliated cell | 5 studies | 19% ± 2% | |
retinal cone cell | 4 studies | 27% ± 9% | |
GABAergic neuron | 3 studies | 34% ± 13% | |
glutamatergic neuron | 3 studies | 41% ± 18% | |
astrocyte | 3 studies | 22% ± 4% | |
oligodendrocyte precursor cell | 3 studies | 26% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 28% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 4511.67 | 258 / 258 | 100% | 33.31 | 230 / 230 |
liver | 100% | 3416.47 | 226 / 226 | 100% | 24.93 | 406 / 406 |
prostate | 100% | 4071.62 | 245 / 245 | 100% | 15.58 | 502 / 502 |
uterus | 100% | 6007.85 | 170 / 170 | 100% | 14.50 | 459 / 459 |
skin | 100% | 4598.56 | 1808 / 1809 | 100% | 19.54 | 472 / 472 |
esophagus | 100% | 4352.25 | 1444 / 1445 | 100% | 15.41 | 183 / 183 |
breast | 100% | 8023.84 | 459 / 459 | 100% | 14.98 | 1116 / 1118 |
intestine | 100% | 5448.87 | 966 / 966 | 100% | 21.06 | 526 / 527 |
bladder | 100% | 6080.05 | 21 / 21 | 100% | 15.23 | 502 / 504 |
thymus | 100% | 3160.39 | 651 / 653 | 100% | 19.18 | 604 / 605 |
lung | 99% | 2846.14 | 572 / 578 | 100% | 13.11 | 1152 / 1155 |
stomach | 98% | 2851.85 | 352 / 359 | 100% | 19.07 | 286 / 286 |
brain | 97% | 5767.18 | 2554 / 2642 | 100% | 30.80 | 705 / 705 |
pancreas | 97% | 2198.84 | 317 / 328 | 100% | 18.90 | 178 / 178 |
ovary | 100% | 4766.83 | 180 / 180 | 96% | 8.06 | 414 / 430 |
kidney | 96% | 1913.66 | 85 / 89 | 100% | 13.88 | 898 / 901 |
adipose | 100% | 8656.60 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4984.69 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 26.10 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 16.80 | 29 / 29 |
muscle | 100% | 7233.25 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2008.86 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 14.23 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.37 | 1 / 1 |
heart | 97% | 3215.36 | 832 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 42% | 883.67 | 393 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006974 | Biological process | DNA damage response |
GO_0016567 | Biological process | protein ubiquitination |
GO_0031145 | Biological process | anaphase-promoting complex-dependent catabolic process |
GO_0031146 | Biological process | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
GO_0031571 | Biological process | mitotic G1 DNA damage checkpoint signaling |
GO_0019005 | Cellular component | SCF ubiquitin ligase complex |
GO_0005829 | Cellular component | cytosol |
GO_0043025 | Cellular component | neuronal cell body |
GO_0005515 | Molecular function | protein binding |
GO_0030332 | Molecular function | cyclin binding |
Gene name | FBXO31 |
Protein name | F-box only protein 31 F-box protein 31 |
Synonyms | FBX31 hCG_1980666 PP2386 FBX14 |
Description | FUNCTION: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor. . |
Accessions | ENST00000311635.12 [Q5XUX0-1] A0A1B0GV77 ENST00000618298.6 ENST00000636077.2 Q5XUX0 A0A0C4DGU8 H3BQG7 ENST00000565593.1 |