Name | Number of supported studies | Average coverage | |
---|---|---|---|
retinal rod cell | 7 studies | 28% ± 5% | |
endothelial cell | 6 studies | 21% ± 4% | |
glutamatergic neuron | 6 studies | 37% ± 19% | |
retinal cone cell | 6 studies | 41% ± 14% | |
GABAergic neuron | 6 studies | 34% ± 14% | |
epithelial cell | 5 studies | 32% ± 8% | |
interneuron | 4 studies | 42% ± 22% | |
ciliated cell | 3 studies | 19% ± 3% | |
dendritic cell | 3 studies | 21% ± 2% | |
basal cell | 3 studies | 28% ± 13% | |
transit amplifying cell | 3 studies | 29% ± 15% | |
astrocyte | 3 studies | 25% ± 7% | |
neuron | 3 studies | 23% ± 4% | |
oligodendrocyte | 3 studies | 22% ± 3% | |
oligodendrocyte precursor cell | 3 studies | 23% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 1405.47 | 459 / 459 | 100% | 10.45 | 1118 / 1118 |
esophagus | 100% | 1405.12 | 1445 / 1445 | 100% | 7.63 | 183 / 183 |
lung | 100% | 1357.88 | 578 / 578 | 100% | 8.59 | 1155 / 1155 |
bladder | 100% | 1502.00 | 21 / 21 | 100% | 8.46 | 503 / 504 |
prostate | 100% | 2013.31 | 245 / 245 | 100% | 8.89 | 501 / 502 |
stomach | 100% | 1341.77 | 359 / 359 | 100% | 7.27 | 285 / 286 |
uterus | 100% | 1590.09 | 170 / 170 | 100% | 9.35 | 457 / 459 |
pancreas | 100% | 1757.71 | 328 / 328 | 99% | 6.80 | 177 / 178 |
intestine | 100% | 1481.28 | 966 / 966 | 99% | 7.95 | 524 / 527 |
liver | 100% | 1330.91 | 226 / 226 | 99% | 7.24 | 403 / 406 |
kidney | 100% | 1373.99 | 89 / 89 | 99% | 7.73 | 894 / 901 |
thymus | 100% | 1589.33 | 653 / 653 | 99% | 8.14 | 600 / 605 |
ovary | 100% | 1571.03 | 180 / 180 | 99% | 6.15 | 425 / 430 |
skin | 100% | 2086.98 | 1809 / 1809 | 99% | 10.98 | 466 / 472 |
brain | 99% | 1415.61 | 2621 / 2642 | 99% | 6.46 | 696 / 705 |
adrenal gland | 100% | 1828.92 | 258 / 258 | 96% | 6.40 | 220 / 230 |
adipose | 100% | 1123.00 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 8.16 | 29 / 29 |
spleen | 100% | 1310.30 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 8.04 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.61 | 1 / 1 |
blood vessel | 100% | 1331.22 | 1333 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 931.84 | 800 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 870.83 | 834 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 91% | 5.89 | 73 / 80 |
peripheral blood | 63% | 968.27 | 586 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006913 | Biological process | nucleocytoplasmic transport |
GO_0032436 | Biological process | positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
GO_0048742 | Biological process | regulation of skeletal muscle fiber development |
GO_0006511 | Biological process | ubiquitin-dependent protein catabolic process |
GO_0036211 | Biological process | protein modification process |
GO_0000209 | Biological process | protein polyubiquitination |
GO_0009267 | Biological process | cellular response to starvation |
GO_0043161 | Biological process | proteasome-mediated ubiquitin-dependent protein catabolic process |
GO_0005829 | Cellular component | cytosol |
GO_0030018 | Cellular component | Z disc |
GO_0005634 | Cellular component | nucleus |
GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | FBXO22 |
Protein name | F-box only protein 22 (F-box protein FBX22p44) F-box protein 22 |
Synonyms | FBX22 |
Description | FUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function. . |
Accessions | ENST00000453211.6 [Q8NEZ5-3] ENST00000561885.1 H3BTR7 H3BUC1 ENST00000569749.5 ENST00000564220.1 ENST00000569054.5 H3BVA4 Q8NEZ5 ENST00000565036.5 H3BRE0 ENST00000569022.1 [Q8NEZ5-2] ENST00000308275.8 [Q8NEZ5-1] H3BTH6 |