FBXL14 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FBXL14 at single-cell level.

II. Expression across tissues

III. Associated gene sets

GO_0006511Biological processubiquitin-dependent protein catabolic process
GO_0031146Biological processSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO_0019005Cellular componentSCF ubiquitin ligase complex
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0004842Molecular functionubiquitin-protein transferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFBXL14
Protein nameF-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14)
SynonymsFBL14
DescriptionFUNCTION: Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1. .

AccessionsENST00000339235.4
Q8N1E6