FBLN5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046903Biological processsecretion
GO_0048251Biological processelastic fiber assembly
GO_2000121Biological processregulation of removal of superoxide radicals
GO_0034394Biological processprotein localization to cell surface
GO_0007160Biological processcell-matrix adhesion
GO_0005615Cellular componentextracellular space
GO_0070062Cellular componentextracellular exosome
GO_0071953Cellular componentelastic fiber
GO_0005576Cellular componentextracellular region
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0031012Cellular componentextracellular matrix
GO_0030023Molecular functionextracellular matrix constituent conferring elasticity
GO_0042803Molecular functionprotein homodimerization activity
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding
GO_0005178Molecular functionintegrin binding

IV. Literature review

[source]
Gene nameFBLN5
Protein nameFibulin 5
Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50)
Fibulin-5
SynonymshCG_21251
DANCE
UNQ184/PRO210
DescriptionFUNCTION: Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN . Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling . May act as an adapter that mediates the interaction between FBN1 and ELN . .

AccessionsENST00000706676.1
A0A9L9PX66
A0A9L9PXD9
G3V3Y2
G3XA98
G3V4U0
ENST00000554468.5
Q9UBX5
ENST00000706677.1
ENST00000557088.6
ENST00000557570.2
ENST00000706680.1
ENST00000342058.9
G3V2P8
ENST00000267620.14
A0A9L9PY85
ENST00000706681.1
ENST00000706679.1
ENST00000556154.5
G3V329