Name | Number of supported studies | Average coverage | |
---|---|---|---|
smooth muscle cell | 17 studies | 24% ± 5% | |
pericyte | 16 studies | 24% ± 8% | |
fibroblast | 14 studies | 24% ± 7% | |
epithelial cell | 8 studies | 25% ± 10% | |
myofibroblast cell | 5 studies | 32% ± 9% | |
enterocyte | 5 studies | 20% ± 2% | |
endothelial cell of artery | 4 studies | 29% ± 5% | |
goblet cell | 4 studies | 18% ± 2% | |
connective tissue cell | 4 studies | 27% ± 5% | |
endothelial cell | 3 studies | 24% ± 5% | |
brush cell | 3 studies | 22% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4158.49 | 1443 / 1445 | 100% | 88.94 | 183 / 183 |
intestine | 100% | 7200.03 | 966 / 966 | 100% | 69.92 | 525 / 527 |
prostate | 100% | 7637.33 | 245 / 245 | 100% | 62.85 | 500 / 502 |
lung | 100% | 5621.65 | 576 / 578 | 99% | 61.32 | 1139 / 1155 |
bladder | 100% | 6422.38 | 21 / 21 | 98% | 68.97 | 495 / 504 |
uterus | 100% | 8610.95 | 170 / 170 | 98% | 76.36 | 450 / 459 |
stomach | 98% | 3739.04 | 351 / 359 | 100% | 75.71 | 286 / 286 |
breast | 100% | 4208.74 | 458 / 459 | 97% | 55.71 | 1082 / 1118 |
pancreas | 96% | 2378.67 | 316 / 328 | 99% | 98.37 | 177 / 178 |
ovary | 99% | 5607.38 | 179 / 180 | 92% | 42.24 | 396 / 430 |
thymus | 99% | 2798.73 | 645 / 653 | 80% | 19.33 | 482 / 605 |
kidney | 89% | 3743.88 | 79 / 89 | 83% | 35.78 | 745 / 901 |
skin | 92% | 2373.71 | 1667 / 1809 | 76% | 32.96 | 361 / 472 |
adrenal gland | 96% | 2595.88 | 247 / 258 | 56% | 17.02 | 128 / 230 |
blood vessel | 100% | 39971.56 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 4251.28 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 95.85 | 1 / 1 |
adipose | 100% | 4408.20 | 1198 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 32.15 | 77 / 80 |
tonsil | 0% | 0 | 0 / 0 | 96% | 54.69 | 43 / 45 |
heart | 95% | 4527.59 | 818 / 861 | 0% | 0 | 0 / 0 |
liver | 9% | 160.81 | 21 / 226 | 56% | 24.26 | 227 / 406 |
lymph node | 0% | 0 | 0 / 0 | 34% | 6.93 | 10 / 29 |
brain | 1% | 16.67 | 24 / 2642 | 27% | 9.35 | 191 / 705 |
muscle | 7% | 116.20 | 56 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 5.53 | 4 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0033623 | Biological process | regulation of integrin activation |
GO_0008360 | Biological process | regulation of cell shape |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0030054 | Cellular component | cell junction |
GO_0001725 | Cellular component | stress fiber |
GO_0005829 | Cellular component | cytosol |
GO_0071944 | Cellular component | cell periphery |
GO_0005737 | Cellular component | cytoplasm |
GO_0001650 | Cellular component | fibrillar center |
GO_0005925 | Cellular component | focal adhesion |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0031005 | Molecular function | filamin binding |
Gene name | FBLIM1 |
Protein name | Filamin binding LIM protein 1 Filamin-binding LIM protein 1 (FBLP-1) (Migfilin) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) |
Synonyms | FBLP1 |
Description | FUNCTION: Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion. . |
Accessions | Q8WUP2 ENST00000332305.5 [Q8WUP2-3] ENST00000431771.6 ENST00000510393.5 ENST00000502638.5 D6R9V9 D6RA19 D6R9I4 ENST00000496928.6 ENST00000510929.5 D6RAI8 ENST00000502739.5 ENST00000441801.6 [Q8WUP2-2] ENST00000508310.5 E7EPI5 ENST00000375766.8 [Q8WUP2-1] ENST00000483633.6 E7EN81 D6RAI6 Q5VVD3 ENST00000375771.5 [Q8WUP2-1] ENST00000430076.5 E7EWE8 |