FBLIM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0033623Biological processregulation of integrin activation
GO_0008360Biological processregulation of cell shape
GO_0098609Biological processcell-cell adhesion
GO_0030054Cellular componentcell junction
GO_0001725Cellular componentstress fiber
GO_0005829Cellular componentcytosol
GO_0071944Cellular componentcell periphery
GO_0005737Cellular componentcytoplasm
GO_0001650Cellular componentfibrillar center
GO_0005925Cellular componentfocal adhesion
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0031005Molecular functionfilamin binding

IV. Literature review

[source]
Gene nameFBLIM1
Protein nameFilamin binding LIM protein 1
Filamin-binding LIM protein 1 (FBLP-1) (Migfilin) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein)
SynonymsFBLP1
DescriptionFUNCTION: Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion. .

AccessionsQ8WUP2
ENST00000332305.5 [Q8WUP2-3]
ENST00000431771.6
ENST00000510393.5
ENST00000502638.5
D6R9V9
D6RA19
D6R9I4
ENST00000496928.6
ENST00000510929.5
D6RAI8
ENST00000502739.5
ENST00000441801.6 [Q8WUP2-2]
ENST00000508310.5
E7EPI5
ENST00000375766.8 [Q8WUP2-1]
ENST00000483633.6
E7EN81
D6RAI6
Q5VVD3
ENST00000375771.5 [Q8WUP2-1]
ENST00000430076.5
E7EWE8