FASTKD3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FASTKD3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FASTKD3 at tissue level.

III. Associated gene sets

GO_0044528Biological processregulation of mitochondrial mRNA stability
GO_0070131Biological processpositive regulation of mitochondrial translation
GO_0000963Biological processmitochondrial RNA processing
GO_0033617Biological processmitochondrial cytochrome c oxidase assembly
GO_0035770Cellular componentribonucleoprotein granule
GO_0005739Cellular componentmitochondrion
GO_0005654Cellular componentnucleoplasm
GO_0005759Cellular componentmitochondrial matrix
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameFASTKD3
Protein nameFAST kinase domain-containing protein 3, mitochondrial
FAST kinase domains 3
Synonyms
DescriptionFUNCTION: Required for normal mitochondrial respiration . Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity . .

AccessionsENST00000507572.1
D6RB04
ENST00000504695.1
Q14CZ7
D6RAR6
D6RHY4
ENST00000264669.10
ENST00000507036.1
ENST00000511261.5
D6RC07