FAR2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010025Biological processwax biosynthetic process
GO_0035336Biological processlong-chain fatty-acyl-CoA metabolic process
GO_0005778Cellular componentperoxisomal membrane
GO_0005777Cellular componentperoxisome
GO_0102965Molecular functionalcohol-forming long-chain fatty acyl-CoA reductase activity
GO_0016491Molecular functionoxidoreductase activity
GO_0080019Molecular functionalcohol-forming very long-chain fatty acyl-CoA reductase activity

IV. Literature review

[source]
Gene nameFAR2
Protein nameFatty acyl-CoA reductase (EC 1.2.1.84)
Fatty acyl-CoA reductase 2 (EC 1.2.1.84) (Male sterility domain-containing protein 1)
SynonymsMLSTD1
DescriptionFUNCTION: Catalyzes the reduction of saturated but not unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. A lower activity can be observed with shorter fatty acyl-CoA substrates . It may play a role in the production of ether lipids/plasmalogens and wax monoesters which synthesis requires fatty alcohols as substrates (By similarity). .

FUNCTION: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. .

FUNCTION: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. .

FUNCTION: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. .

FUNCTION: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. .

FUNCTION: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. .

FUNCTION: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. .

FUNCTION: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. .

FUNCTION: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. .

FUNCTION: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. .

AccessionsENST00000547759.2
ENST00000686305.1
H0YIE0
H0YHP1
ENST00000686419.1
A0A8I5KVC4
A0A8I5KXF4
A0A8I5KUM2
ENST00000182377.8 [Q96K12-1]
ENST00000691273.1
ENST00000536681.8 [Q96K12-1]
ENST00000690162.1 [Q96K12-2]
ENST00000693163.1
ENST00000692223.1
F8VPF2
ENST00000551193.2
A0A8I5KS86
ENST00000552137.1
F8VX60
A0A8I5KQJ4
ENST00000547116.5 [Q96K12-2]
Q96K12
ENST00000551451.6