Insufficient scRNA-seq data for expression of FANCG at single-cell level.
Insufficient scRNA-seq data for expression of FANCG at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| uterus | 100% | 959.97 | 170 / 170 | 68% | 1.24 | 313 / 459 |
| bladder | 100% | 716.29 | 21 / 21 | 48% | 0.89 | 240 / 504 |
| intestine | 100% | 734.36 | 966 / 966 | 46% | 0.98 | 240 / 527 |
| stomach | 100% | 599.64 | 359 / 359 | 38% | 0.74 | 110 / 286 |
| esophagus | 100% | 659.81 | 1441 / 1445 | 34% | 0.54 | 62 / 183 |
| ovary | 100% | 961.33 | 180 / 180 | 33% | 0.52 | 142 / 430 |
| brain | 99% | 809.35 | 2624 / 2642 | 32% | 0.53 | 225 / 705 |
| lung | 100% | 647.81 | 576 / 578 | 23% | 0.40 | 265 / 1155 |
| breast | 100% | 719.80 | 459 / 459 | 17% | 0.25 | 185 / 1118 |
| thymus | 100% | 813.05 | 653 / 653 | 12% | 0.24 | 74 / 605 |
| pancreas | 100% | 688.33 | 328 / 328 | 11% | 0.16 | 20 / 178 |
| skin | 100% | 1120.21 | 1809 / 1809 | 8% | 0.11 | 36 / 472 |
| kidney | 100% | 621.08 | 89 / 89 | 4% | 0.06 | 37 / 901 |
| adrenal gland | 100% | 608.17 | 258 / 258 | 3% | 0.04 | 6 / 230 |
| prostate | 100% | 841.90 | 245 / 245 | 2% | 0.03 | 9 / 502 |
| spleen | 100% | 1143.32 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.55 | 1 / 1 |
| adipose | 100% | 646.08 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| liver | 96% | 323.69 | 216 / 226 | 4% | 0.06 | 17 / 406 |
| blood vessel | 99% | 478.51 | 1328 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 87% | 765.33 | 809 / 929 | 0% | 0 | 0 / 0 |
| heart | 85% | 250.35 | 736 / 861 | 0% | 0 | 0 / 0 |
| muscle | 68% | 155.82 | 548 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 60% | 1.09 | 27 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 52% | 0.85 | 15 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006974 | Biological process | DNA damage response |
| GO_0006281 | Biological process | DNA repair |
| GO_0007005 | Biological process | mitochondrion organization |
| GO_0009314 | Biological process | response to radiation |
| GO_0036297 | Biological process | interstrand cross-link repair |
| GO_0007286 | Biological process | spermatid development |
| GO_0001541 | Biological process | ovarian follicle development |
| GO_0043240 | Cellular component | Fanconi anaemia nuclear complex |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0000785 | Cellular component | chromatin |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005515 | Molecular function | protein binding |
| GO_0003684 | Molecular function | damaged DNA binding |
| Gene name | FANCG |
| Protein name | Truncated Fanconi anemia group G protein Fanconi anemia complementation group G isoform 1 (Fanconi anemia, complementation group G) (cDNA, FLJ93448, Homo sapiens Fanconi anemia, complementation group G (FANCG), mRNA) Fanconi anemia complementation group G isoform 6 FA complementation group G Fanconi anemia complementation group G isoform 5 Fanconi anemia group G protein (Protein FACG) (DNA repair protein XRCC9) Fanconi anemia complementation group G isoform 3 Fanconi anemia complementation group G Fanconi anemia group G protein |
| Synonyms | hCG_20469 XRCC9 |
| Description | FUNCTION: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene. |
| Accessions | ENST00000696710.1 A0A0K2GN97 ENST00000425676.5 O15287 A0A0S2Z3W0 ENST00000448890.1 ENST00000696713.1 A0A8Q3SJ04 F8WC08 ENST00000448890.2 ENST00000378643.8 ENST00000696708.1 A0A8Q3WMK6 A0A8Q3WLH9 ENST00000696703.1 A0A0S2Z4A7 Q53XM5 ENST00000696702.1 A0A0S2Z3R2 A0A0S2Z3S1 ENST00000696715.1 C9JSE3 |