I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 18% ± 1% | |
| glutamatergic neuron | 3 studies | 27% ± 8% | |
| transit amplifying cell | 3 studies | 49% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 18% ± 1% | |
| glutamatergic neuron | 3 studies | 27% ± 8% | |
| transit amplifying cell | 3 studies | 49% ± 20% |
Insufficient scRNA-seq data for expression of FANCA at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 99% | 413.40 | 575 / 578 | 91% | 6.64 | 1050 / 1155 |
| skin | 99% | 757.02 | 1794 / 1809 | 91% | 5.75 | 430 / 472 |
| stomach | 77% | 267.40 | 276 / 359 | 96% | 8.89 | 275 / 286 |
| ovary | 87% | 152.89 | 156 / 180 | 86% | 4.98 | 368 / 430 |
| intestine | 72% | 415.95 | 700 / 966 | 96% | 8.66 | 508 / 527 |
| uterus | 72% | 130.28 | 123 / 170 | 95% | 10.21 | 436 / 459 |
| bladder | 71% | 140.33 | 15 / 21 | 93% | 7.49 | 468 / 504 |
| breast | 90% | 183.38 | 412 / 459 | 70% | 3.92 | 785 / 1118 |
| esophagus | 60% | 323.06 | 865 / 1445 | 100% | 10.90 | 183 / 183 |
| pancreas | 79% | 123.56 | 258 / 328 | 69% | 3.04 | 123 / 178 |
| liver | 97% | 313.10 | 220 / 226 | 48% | 1.87 | 194 / 406 |
| thymus | 96% | 216.58 | 629 / 653 | 30% | 1.23 | 183 / 605 |
| brain | 78% | 226.21 | 2069 / 2642 | 45% | 2.41 | 320 / 705 |
| kidney | 81% | 180.00 | 72 / 89 | 31% | 1.06 | 281 / 901 |
| adrenal gland | 96% | 203.08 | 247 / 258 | 16% | 0.75 | 36 / 230 |
| spleen | 100% | 787.15 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 9.30 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.74 | 1 / 1 |
| prostate | 90% | 200.83 | 220 / 245 | 7% | 0.23 | 37 / 502 |
| peripheral blood | 97% | 1027.58 | 902 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 16.90 | 28 / 29 |
| adipose | 88% | 164.69 | 1061 / 1204 | 0% | 0 | 0 / 0 |
| heart | 58% | 83.90 | 497 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 35% | 48.93 | 463 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 12% | 13.22 | 97 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 9% | 0.21 | 7 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0008584 | Biological process | male gonad development |
| GO_1905936 | Biological process | regulation of germ cell proliferation |
| GO_0006281 | Biological process | DNA repair |
| GO_0036297 | Biological process | interstrand cross-link repair |
| GO_2000348 | Biological process | regulation of CD40 signaling pathway |
| GO_0008585 | Biological process | female gonad development |
| GO_0050727 | Biological process | regulation of inflammatory response |
| GO_0045589 | Biological process | regulation of regulatory T cell differentiation |
| GO_0007140 | Biological process | male meiotic nuclear division |
| GO_0065003 | Biological process | protein-containing complex assembly |
| GO_0043240 | Cellular component | Fanconi anaemia nuclear complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0000785 | Cellular component | chromatin |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | FANCA |
| Protein name | Alternative protein FANCA FA complementation group A (FANCA protein) Fanconi anemia, complementation group A FANCA protein Fanconi anemia group A protein (Protein FACA) FA complementation group A |
| Synonyms | FACA FAA FANCH |
| Description | FUNCTION: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. |
| Accessions | ENST00000565582.5 ENST00000389301.8 [O15360-1] ENST00000563513.1 ENST00000564870.1 H3BSA3 F5H8D5 ENST00000567621.6 ENST00000567879.5 ENST00000567205.2 ENST00000568369.6 [O15360-3] ENST00000696294.1 ENST00000696293.1 ENST00000696291.1 ENST00000568626.1 H3BM41 Q86U55 ENST00000389302.7 [O15360-2] H3BV66 A0A8Q3WM51 ENST00000567988.5 H3BNS0 H3BRX3 H3BS84 ENST00000696296.1 A0A8Q3WL48 ENST00000564475.6 A0PJU8 A0A8Q3WL54 ENST00000566409.1 L8E9D3 Q0VAP3 H3BSI9 ENST00000696287.1 H3BQW7 Q0VAP4 A0A8Q3WL53 H3BUI1 A0A8Q3WL60 ENST00000543736.5 A0A8Q3SJ96 A0A8Q3WL82 ENST00000561660.1 ENST00000561722.5 ENST00000696288.1 ENST00000561667.2 H3BT40 O15360 H3BQU1 ENST00000563673.5 A0A8Q3SID5 A0A8Q3WLP8 A0A8Q3SIN0 H3BQX1 Q9Y500 ENST00000696277.1 H3BQU6 Q9Y4Z9 ENST00000696292.1 ENST00000696295.1 A0A8Q3WL44 H3BT53 ENST00000563510.5 ENST00000567510.2 H3BT32 ENST00000534992.5 H3BSL6 ENST00000696286.1 ENST00000563318.1 ENST00000696275.1 [O15360-2] H3BS03 ENST00000567943.1 Q9Y4Z8 |
