F5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of F5 at tissue level.

III. Associated gene sets

GO_0008015Biological processblood circulation
GO_0007596Biological processblood coagulation
GO_0032571Biological processresponse to vitamin K
GO_0033116Cellular componentendoplasmic reticulum-Golgi intermediate compartment membrane
GO_0005615Cellular componentextracellular space
GO_0031091Cellular componentplatelet alpha granule
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_1903561Cellular componentextracellular vesicle
GO_0031093Cellular componentplatelet alpha granule lumen
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0030134Cellular componentCOPII-coated ER to Golgi transport vesicle
GO_0005507Molecular functioncopper ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameF5
Protein nameCoagulation factor V (Activated protein C cofactor) (Proaccelerin, labile factor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain]
Coagulation factor V
Synonyms
DescriptionFUNCTION: Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.

AccessionsQ15430
ENST00000367797.9
C8C1T0
ENST00000367796.3
Q8IUL1
P12259
A0A0A0MRJ7
C8C1T1
A0A4P8D7E7
A0A4V1DVZ0
A0A4P8D7E0