Name | Number of supported studies | Average coverage | |
---|---|---|---|
hepatocyte | 6 studies | 58% ± 29% | |
regulatory T cell | 5 studies | 18% ± 2% | |
classical monocyte | 3 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of F5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 10413.55 | 226 / 226 | 97% | 169.46 | 395 / 406 |
prostate | 62% | 362.87 | 151 / 245 | 83% | 31.27 | 416 / 502 |
pancreas | 53% | 173.58 | 173 / 328 | 84% | 26.46 | 149 / 178 |
lung | 93% | 416.05 | 540 / 578 | 35% | 6.30 | 406 / 1155 |
kidney | 91% | 413.09 | 81 / 89 | 30% | 7.04 | 271 / 901 |
spleen | 96% | 832.95 | 232 / 241 | 0% | 0 | 0 / 0 |
bladder | 67% | 358.33 | 14 / 21 | 28% | 4.51 | 141 / 504 |
thymus | 60% | 198.72 | 393 / 653 | 27% | 6.45 | 165 / 605 |
heart | 86% | 670.66 | 740 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 83% | 3662.86 | 770 / 929 | 0% | 0 | 0 / 0 |
stomach | 33% | 78.11 | 120 / 359 | 47% | 11.60 | 134 / 286 |
skin | 56% | 321.88 | 1018 / 1809 | 22% | 10.07 | 102 / 472 |
adipose | 70% | 295.97 | 848 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 66% | 299.96 | 885 / 1335 | 0% | 0 | 0 / 0 |
brain | 13% | 27.23 | 347 / 2642 | 43% | 11.97 | 304 / 705 |
breast | 47% | 234.39 | 214 / 459 | 9% | 0.85 | 98 / 1118 |
intestine | 17% | 33.05 | 165 / 966 | 33% | 7.56 | 176 / 527 |
esophagus | 10% | 22.60 | 145 / 1445 | 40% | 18.37 | 74 / 183 |
lymph node | 0% | 0 | 0 / 0 | 41% | 3.21 | 12 / 29 |
tonsil | 0% | 0 | 0 / 0 | 20% | 0.89 | 9 / 45 |
uterus | 9% | 22.44 | 15 / 170 | 11% | 2.10 | 50 / 459 |
adrenal gland | 2% | 3.13 | 4 / 258 | 3% | 0.42 | 6 / 230 |
eye | 0% | 0 | 0 / 0 | 4% | 0.29 | 3 / 80 |
ovary | 2% | 2.25 | 3 / 180 | 2% | 0.09 | 7 / 430 |
muscle | 2% | 3.09 | 14 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0008015 | Biological process | blood circulation |
GO_0007596 | Biological process | blood coagulation |
GO_0032571 | Biological process | response to vitamin K |
GO_0033116 | Cellular component | endoplasmic reticulum-Golgi intermediate compartment membrane |
GO_0005615 | Cellular component | extracellular space |
GO_0031091 | Cellular component | platelet alpha granule |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_1903561 | Cellular component | extracellular vesicle |
GO_0031093 | Cellular component | platelet alpha granule lumen |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0030134 | Cellular component | COPII-coated ER to Golgi transport vesicle |
GO_0005507 | Molecular function | copper ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | F5 |
Protein name | Coagulation factor V (Activated protein C cofactor) (Proaccelerin, labile factor) [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Coagulation factor V |
Synonyms | |
Description | FUNCTION: Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin. |
Accessions | Q15430 ENST00000367797.9 C8C1T0 ENST00000367796.3 Q8IUL1 P12259 A0A0A0MRJ7 C8C1T1 A0A4P8D7E7 A0A4V1DVZ0 A0A4P8D7E0 |