EPS15L1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016197Biological processendosomal transport
GO_0006897Biological processendocytosis
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0030132Cellular componentclathrin coat of coated pit
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0045296Molecular functioncadherin binding
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameEPS15L1
Protein nameEpidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)
Epidermal growth factor receptor pathway substrate 15 like 1
EPS15L1 protein
SynonymsEPS15R
DescriptionFUNCTION: Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. .

AccessionsENST00000597937.5 [Q9UBC2-4]
ENST00000535753.6 [Q9UBC2-3]
ENST00000593760.5
M0QY01
ENST00000596037.5
ENST00000248070.10 [Q9UBC2-1]
ENST00000592031.5
K7EJR2
M0R2S2
ENST00000602009.5
ENST00000602022.5 [Q9UBC2-3]
M0R1V5
M0R165
Q9UBC2
A5PKY0
M0R330
ENST00000602151.1
M0QX30
ENST00000594851.5
M0R3I1
ENST00000594975.5
ENST00000455140.7 [Q9UBC2-2]
ENST00000599790.1