Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 16 studies | 33% ± 19% | |
endothelial cell | 10 studies | 30% ± 13% | |
glutamatergic neuron | 8 studies | 40% ± 25% | |
microglial cell | 7 studies | 26% ± 8% | |
oligodendrocyte precursor cell | 7 studies | 28% ± 11% | |
adipocyte | 7 studies | 22% ± 5% | |
GABAergic neuron | 7 studies | 44% ± 21% | |
interneuron | 6 studies | 39% ± 23% | |
oligodendrocyte | 6 studies | 24% ± 5% | |
neuron | 5 studies | 29% ± 13% | |
macrophage | 5 studies | 26% ± 6% | |
cardiac muscle cell | 5 studies | 38% ± 8% | |
fibroblast | 5 studies | 21% ± 5% | |
granule cell | 4 studies | 28% ± 12% | |
epithelial cell | 4 studies | 27% ± 9% | |
ciliated cell | 4 studies | 18% ± 3% | |
endothelial cell of lymphatic vessel | 4 studies | 27% ± 8% | |
GABAergic interneuron | 3 studies | 26% ± 8% | |
B cell | 3 studies | 17% ± 2% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 18% ± 2% | |
natural killer cell | 3 studies | 16% ± 1% | |
amacrine cell | 3 studies | 23% ± 2% | |
retina horizontal cell | 3 studies | 21% ± 1% | |
abnormal cell | 3 studies | 23% ± 8% | |
pericyte | 3 studies | 20% ± 5% | |
basal cell | 3 studies | 25% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 2873.52 | 21 / 21 | 100% | 15.58 | 504 / 504 |
esophagus | 100% | 2910.27 | 1445 / 1445 | 100% | 19.38 | 183 / 183 |
kidney | 100% | 2362.39 | 89 / 89 | 100% | 14.77 | 901 / 901 |
ovary | 100% | 3001.31 | 180 / 180 | 100% | 19.59 | 430 / 430 |
prostate | 100% | 2697.40 | 245 / 245 | 100% | 15.02 | 502 / 502 |
stomach | 100% | 1962.17 | 359 / 359 | 100% | 14.44 | 286 / 286 |
thymus | 100% | 2745.53 | 653 / 653 | 100% | 15.89 | 605 / 605 |
uterus | 100% | 3165.30 | 170 / 170 | 100% | 17.63 | 459 / 459 |
skin | 100% | 3250.90 | 1808 / 1809 | 100% | 20.21 | 472 / 472 |
lung | 100% | 2414.72 | 577 / 578 | 100% | 16.14 | 1155 / 1155 |
intestine | 100% | 2536.83 | 966 / 966 | 100% | 13.84 | 526 / 527 |
brain | 100% | 2907.86 | 2634 / 2642 | 100% | 22.51 | 705 / 705 |
breast | 100% | 2437.87 | 459 / 459 | 100% | 25.07 | 1114 / 1118 |
pancreas | 100% | 1185.12 | 327 / 328 | 99% | 13.49 | 177 / 178 |
adrenal gland | 100% | 2256.95 | 258 / 258 | 99% | 16.01 | 228 / 230 |
liver | 98% | 975.50 | 221 / 226 | 93% | 7.63 | 379 / 406 |
adipose | 100% | 2480.08 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2421.94 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 20.56 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 18.11 | 29 / 29 |
muscle | 100% | 7374.65 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2539.20 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 17.21 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 8.95 | 1 / 1 |
peripheral blood | 99% | 3581.19 | 923 / 929 | 0% | 0 | 0 / 0 |
heart | 99% | 3945.72 | 850 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0016197 | Biological process | endosomal transport |
GO_0006897 | Biological process | endocytosis |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0030132 | Cellular component | clathrin coat of coated pit |
GO_0016020 | Cellular component | membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0045296 | Molecular function | cadherin binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | EPS15L1 |
Protein name | Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) Epidermal growth factor receptor pathway substrate 15 like 1 EPS15L1 protein |
Synonyms | EPS15R |
Description | FUNCTION: Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. . |
Accessions | ENST00000597937.5 [Q9UBC2-4] ENST00000535753.6 [Q9UBC2-3] ENST00000593760.5 M0QY01 ENST00000596037.5 ENST00000248070.10 [Q9UBC2-1] ENST00000592031.5 K7EJR2 M0R2S2 ENST00000602009.5 ENST00000602022.5 [Q9UBC2-3] M0R1V5 M0R165 Q9UBC2 A5PKY0 M0R330 ENST00000602151.1 M0QX30 ENST00000594851.5 M0R3I1 ENST00000594975.5 ENST00000455140.7 [Q9UBC2-2] ENST00000599790.1 |