EPN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0048568Biological processembryonic organ development
GO_0006897Biological processendocytosis
GO_0007219Biological processNotch signaling pathway
GO_0001701Biological processin utero embryonic development
GO_1903671Biological processnegative regulation of sprouting angiogenesis
GO_0007565Biological processfemale pregnancy
GO_0030125Cellular componentclathrin vesicle coat
GO_0005905Cellular componentclathrin-coated pit
GO_0005768Cellular componentendosome
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005634Cellular componentnucleus
GO_0030276Molecular functionclathrin binding
GO_0140313Molecular functionmolecular sequestering activity
GO_0005515Molecular functionprotein binding
GO_0005543Molecular functionphospholipid binding

IV. Literature review

[source]
Gene nameEPN1
Protein nameEpsin 1
Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1)
Synonyms
DescriptionFUNCTION: Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis . .

AccessionsENST00000589704.1
ENST00000411543.6 [Q9Y6I3-1]
Q9Y6I3
K7EMP4
ENST00000270460.11 [Q9Y6I3-2]
ENST00000085079.11 [Q9Y6I3-3]