ENTREP1 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	13 studies	50% ± 22%	Explore
type I pneumocyte	8 studies	44% ± 14%	Explore
endothelial cell of lymphatic vessel	8 studies	34% ± 14%	Explore
cardiac muscle cell	5 studies	28% ± 6%	Explore
endothelial cell	3 studies	30% ± 8%	Explore
club cell	3 studies	28% ± 6%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of ENTREP1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	2873.69	244 / 245	98%	21.95	491 / 502
thymus	100%	13287.76	653 / 653	97%	33.61	588 / 605
brain	88%	1416.79	2331 / 2642	95%	21.57	673 / 705
breast	98%	3264.71	452 / 459	52%	4.80	579 / 1118
skin	72%	1727.64	1303 / 1809	74%	7.20	349 / 472
lung	99%	2619.50	570 / 578	35%	2.54	403 / 1155
ovary	100%	5059.56	180 / 180	20%	1.17	88 / 430
stomach	99%	1978.75	354 / 359	19%	1.95	54 / 286
esophagus	98%	2073.79	1416 / 1445	19%	1.11	34 / 183
adrenal gland	86%	770.91	223 / 258	29%	1.73	67 / 230
uterus	99%	1505.44	168 / 170	16%	1.41	74 / 459
bladder	100%	1643.10	21 / 21	7%	0.41	37 / 504
kidney	87%	656.20	77 / 89	15%	1.93	136 / 901
eye	0%	0	0 / 0	100%	28.11	80 / 80
muscle	100%	3736.04	801 / 803	0%	0	0 / 0
heart	95%	1449.65	821 / 861	0%	0	0 / 0
adipose	93%	1144.50	1114 / 1204	0%	0	0 / 0
pancreas	74%	732.07	242 / 328	16%	0.80	29 / 178
intestine	77%	1021.24	747 / 966	6%	0.36	33 / 527
blood vessel	71%	585.03	952 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	18%	1.70	8 / 45
spleen	2%	10.20	5 / 241	0%	0	0 / 0
liver	0%	0	0 / 226	0%	0.02	2 / 406
peripheral blood	0%	1.84	2 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0022401	Biological process	negative adaptation of signaling pathway
GO_0038160	Biological process	CXCL12-activated CXCR4 signaling pathway
GO_0031623	Biological process	receptor internalization
GO_0008150	Biological process	biological_process
GO_0005575	Cellular component	cellular_component
GO_0031901	Cellular component	early endosome membrane
GO_0055038	Cellular component	recycling endosome membrane
GO_0031902	Cellular component	late endosome membrane
GO_0005886	Cellular component	plasma membrane
GO_1990757	Molecular function	ubiquitin ligase activator activity
GO_0005515	Molecular function	protein binding
GO_0003674	Molecular function	molecular_function

Gene name	ENTREP1
Protein name	Endosomal transmembrane epsin interactor 1 (Endosomal transmembrane binding with epsin) Endosomal transmembrane epsin interactor 1
Synonyms	FAM189A2 X123 C9orf61
Description	FUNCTION: Functions as an activator of the E3 ubiquitin protein ligase ITCH in the ubiquitination of the CXCL12-activated CXCR4 receptor. Thereby, triggers CXCR4 endocytosis and desensitization, negatively regulating the CXCL12/CXCR4 signaling pathway. .
Accessions	Q15884 A0A0A0MRU1 ENST00000455972.6 [Q15884-3] ENST00000377216.4 ENST00000257515.12 [Q15884-3] ENST00000303068.14 [Q15884-4]

ENTREP1 report