Insufficient scRNA-seq data for expression of EN2 at single-cell level.
Insufficient scRNA-seq data for expression of EN2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 62% | 15.10 | 1121 / 1809 | 96% | 21.90 | 452 / 472 |
| brain | 91% | 1021.45 | 2416 / 2642 | 61% | 4.01 | 429 / 705 |
| uterus | 75% | 26.91 | 127 / 170 | 52% | 3.00 | 237 / 459 |
| ovary | 99% | 108.84 | 178 / 180 | 6% | 0.52 | 25 / 430 |
| breast | 77% | 17.84 | 352 / 459 | 17% | 0.71 | 192 / 1118 |
| muscle | 86% | 48.72 | 690 / 803 | 0% | 0 | 0 / 0 |
| esophagus | 42% | 6.54 | 611 / 1445 | 37% | 1.91 | 68 / 183 |
| adrenal gland | 66% | 17.19 | 170 / 258 | 13% | 0.57 | 29 / 230 |
| prostate | 36% | 5.41 | 88 / 245 | 40% | 0.90 | 203 / 502 |
| thymus | 71% | 13.66 | 462 / 653 | 0% | 0.01 | 2 / 605 |
| bladder | 43% | 4.76 | 9 / 21 | 28% | 1.30 | 139 / 504 |
| intestine | 36% | 5.58 | 344 / 966 | 30% | 1.69 | 160 / 527 |
| tonsil | 0% | 0 | 0 / 0 | 58% | 3.55 | 26 / 45 |
| stomach | 28% | 4.70 | 101 / 359 | 28% | 1.67 | 81 / 286 |
| eye | 0% | 0 | 0 / 0 | 56% | 2.34 | 45 / 80 |
| adipose | 53% | 9.44 | 639 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 32% | 4.32 | 105 / 328 | 21% | 0.85 | 37 / 178 |
| kidney | 35% | 5.85 | 31 / 89 | 13% | 0.78 | 120 / 901 |
| lung | 9% | 1.02 | 52 / 578 | 34% | 1.77 | 398 / 1155 |
| blood vessel | 30% | 4.19 | 406 / 1335 | 0% | 0 | 0 / 0 |
| heart | 27% | 3.98 | 233 / 861 | 0% | 0 | 0 / 0 |
| liver | 8% | 1.31 | 18 / 226 | 11% | 0.36 | 46 / 406 |
| spleen | 8% | 1.20 | 19 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 2% | 0.43 | 22 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0030902 | Biological process | hindbrain development |
| GO_0030182 | Biological process | neuron differentiation |
| GO_0043524 | Biological process | negative regulation of neuron apoptotic process |
| GO_0048666 | Biological process | neuron development |
| GO_0071542 | Biological process | dopaminergic neuron differentiation |
| GO_0030901 | Biological process | midbrain development |
| GO_1990403 | Biological process | embryonic brain development |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0005730 | Cellular component | nucleolus |
| GO_0001650 | Cellular component | fibrillar center |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Gene name | EN2 |
| Protein name | Homeobox protein engrailed-2 (Homeobox protein en-2) (Hu-En-2) |
| Synonyms | |
| Description | |
| Accessions | ENST00000297375.4 P19622 |