Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 12 studies | 26% ± 10% | |
| fibroblast | 11 studies | 22% ± 9% | |
| oligodendrocyte | 10 studies | 28% ± 11% | |
| glutamatergic neuron | 8 studies | 41% ± 25% | |
| GABAergic neuron | 7 studies | 40% ± 19% | |
| interneuron | 6 studies | 39% ± 22% | |
| microglial cell | 6 studies | 23% ± 6% | |
| astrocyte | 6 studies | 31% ± 11% | |
| B cell | 5 studies | 22% ± 3% | |
| neuron | 5 studies | 28% ± 11% | |
| epithelial cell | 5 studies | 40% ± 14% | |
| oligodendrocyte precursor cell | 5 studies | 32% ± 12% | |
| macrophage | 5 studies | 22% ± 7% | |
| CD4-positive, alpha-beta T cell | 4 studies | 22% ± 4% | |
| hepatocyte | 4 studies | 41% ± 15% | |
| endothelial cell of lymphatic vessel | 4 studies | 20% ± 5% | |
| plasmacytoid dendritic cell | 4 studies | 22% ± 5% | |
| GABAergic interneuron | 3 studies | 21% ± 3% | |
| ciliated cell | 3 studies | 27% ± 5% | |
| lymphocyte | 3 studies | 25% ± 6% | |
| CD8-positive, alpha-beta T cell | 3 studies | 19% ± 3% | |
| club cell | 3 studies | 23% ± 7% | |
| T cell | 3 studies | 17% ± 0% | |
| pericyte | 3 studies | 24% ± 7% | |
| goblet cell | 3 studies | 32% ± 20% | |
| adipocyte | 3 studies | 22% ± 5% | |
| naive B cell | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 4910.75 | 459 / 459 | 100% | 76.39 | 1118 / 1118 |
| prostate | 100% | 5850.18 | 245 / 245 | 100% | 36.44 | 502 / 502 |
| brain | 100% | 3495.27 | 2637 / 2642 | 100% | 23.88 | 705 / 705 |
| ovary | 100% | 7451.51 | 180 / 180 | 100% | 16.47 | 429 / 430 |
| thymus | 100% | 3819.00 | 653 / 653 | 100% | 25.35 | 603 / 605 |
| uterus | 100% | 5180.82 | 170 / 170 | 100% | 18.75 | 457 / 459 |
| bladder | 100% | 4446.62 | 21 / 21 | 99% | 19.34 | 501 / 504 |
| liver | 100% | 3216.66 | 226 / 226 | 99% | 15.68 | 402 / 406 |
| pancreas | 100% | 2745.51 | 328 / 328 | 99% | 15.85 | 176 / 178 |
| lung | 100% | 3327.44 | 577 / 578 | 99% | 19.09 | 1144 / 1155 |
| kidney | 100% | 2865.15 | 89 / 89 | 99% | 21.18 | 890 / 901 |
| esophagus | 100% | 3560.62 | 1445 / 1445 | 98% | 14.34 | 180 / 183 |
| skin | 100% | 4974.84 | 1809 / 1809 | 98% | 28.88 | 464 / 472 |
| stomach | 100% | 3040.73 | 359 / 359 | 98% | 12.98 | 280 / 286 |
| intestine | 100% | 3950.63 | 966 / 966 | 98% | 14.43 | 515 / 527 |
| adrenal gland | 100% | 3702.74 | 258 / 258 | 94% | 20.67 | 216 / 230 |
| adipose | 100% | 3917.26 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3769.04 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 23.13 | 29 / 29 |
| muscle | 100% | 4045.23 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3887.69 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 18.35 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.22 | 1 / 1 |
| heart | 98% | 2681.83 | 846 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 91% | 23.26 | 73 / 80 |
| peripheral blood | 62% | 1711.19 | 579 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0002098 | Biological process | tRNA wobble uridine modification |
| GO_0006368 | Biological process | transcription elongation by RNA polymerase II |
| GO_0046425 | Biological process | regulation of receptor signaling pathway via JAK-STAT |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0006417 | Biological process | regulation of translation |
| GO_0033588 | Cellular component | elongator holoenzyme complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0008023 | Cellular component | transcription elongation factor complex |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0000993 | Molecular function | RNA polymerase II complex binding |
| GO_0019901 | Molecular function | protein kinase binding |
| Gene name | ELP2 |
| Protein name | Elongator acetyltransferase complex subunit 2 Elongator complex protein 2 Elongator complex protein 2 (ELP2) (SHINC-2) (STAT3-interacting protein 1) (StIP1) |
| Synonyms | STATIP1 |
| Description | FUNCTION: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) . The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs . . |
| Accessions | ENST00000540799.1 ENST00000540766.5 ENST00000350494.10 [Q6IA86-5] ENST00000442325.6 [Q6IA86-6] ENST00000539560.5 [Q6IA86-4] ENST00000351393.10 [Q6IA86-3] ENST00000544267.5 ENST00000542824.5 [Q6IA86-2] ENST00000423854.6 [Q6IA86-7] ENST00000542430.5 H0YFW0 ENST00000358232.11 [Q6IA86-1] ENST00000543127.5 F5GX79 ENST00000545632.5 Q6IA86 F5GWY6 K7ER35 F5GYE9 |