ELP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0002098Biological processtRNA wobble uridine modification
GO_0006368Biological processtranscription elongation by RNA polymerase II
GO_0046425Biological processregulation of receptor signaling pathway via JAK-STAT
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0006417Biological processregulation of translation
GO_0033588Cellular componentelongator holoenzyme complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0008023Cellular componenttranscription elongation factor complex
GO_0005737Cellular componentcytoplasm
GO_0000993Molecular functionRNA polymerase II complex binding
GO_0019901Molecular functionprotein kinase binding

IV. Literature review

[source]
Gene nameELP2
Protein nameElongator acetyltransferase complex subunit 2
Elongator complex protein 2
Elongator complex protein 2 (ELP2) (SHINC-2) (STAT3-interacting protein 1) (StIP1)
SynonymsSTATIP1
DescriptionFUNCTION: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) . The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs . .

AccessionsENST00000540799.1
ENST00000540766.5
ENST00000350494.10 [Q6IA86-5]
ENST00000442325.6 [Q6IA86-6]
ENST00000539560.5 [Q6IA86-4]
ENST00000351393.10 [Q6IA86-3]
ENST00000544267.5
ENST00000542824.5 [Q6IA86-2]
ENST00000423854.6 [Q6IA86-7]
ENST00000542430.5
H0YFW0
ENST00000358232.11 [Q6IA86-1]
ENST00000543127.5
F5GX79
ENST00000545632.5
Q6IA86
F5GWY6
K7ER35
F5GYE9