ELMO3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ELMO3 at tissue level.

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0048870Biological processcell motility
GO_0007015Biological processactin filament organization
GO_0006909Biological processphagocytosis
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0017124Molecular functionSH3 domain binding

IV. Literature review

[source]
Gene nameELMO3
Protein nameEngulfment and cell motility 3
Engulfment and cell motility protein 3
Synonyms
DescriptionFUNCTION: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity). .

FUNCTION: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. .

AccessionsENST00000360833.6
I3L4D1
F8W9E7
ENST00000393997.8 [Q96BJ8-1]
ENST00000652269.1 [Q96BJ8-3]
Q96BJ8
ENST00000477898.5 [Q96BJ8-2]
ENST00000571587.6