Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 5 studies | 22% ± 7% |
Insufficient scRNA-seq data for expression of ELMO3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 2840.78 | 328 / 328 | 98% | 74.37 | 174 / 178 |
thymus | 100% | 2693.03 | 652 / 653 | 96% | 71.06 | 578 / 605 |
lung | 97% | 1131.47 | 561 / 578 | 97% | 55.40 | 1117 / 1155 |
prostate | 92% | 2557.50 | 226 / 245 | 99% | 72.95 | 499 / 502 |
kidney | 100% | 2248.96 | 89 / 89 | 91% | 41.53 | 818 / 901 |
stomach | 77% | 2271.25 | 278 / 359 | 96% | 66.40 | 275 / 286 |
breast | 65% | 1197.66 | 299 / 459 | 95% | 45.75 | 1057 / 1118 |
intestine | 55% | 1823.01 | 534 / 966 | 98% | 82.92 | 519 / 527 |
bladder | 57% | 979.90 | 12 / 21 | 94% | 70.82 | 474 / 504 |
esophagus | 42% | 1084.96 | 607 / 1445 | 98% | 56.36 | 179 / 183 |
liver | 86% | 489.02 | 195 / 226 | 45% | 18.28 | 183 / 406 |
uterus | 33% | 226.21 | 56 / 170 | 84% | 50.18 | 385 / 459 |
ovary | 12% | 54.84 | 22 / 180 | 95% | 37.72 | 409 / 430 |
tonsil | 0% | 0 | 0 / 0 | 100% | 50.67 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 66.59 | 1 / 1 |
spleen | 98% | 732.14 | 237 / 241 | 0% | 0 | 0 / 0 |
skin | 72% | 2612.74 | 1305 / 1809 | 9% | 1.98 | 44 / 472 |
adrenal gland | 16% | 67.87 | 41 / 258 | 46% | 12.60 | 106 / 230 |
peripheral blood | 39% | 190.74 | 363 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 31% | 3.97 | 9 / 29 |
adipose | 28% | 142.11 | 341 / 1204 | 0% | 0 | 0 / 0 |
brain | 17% | 122.71 | 448 / 2642 | 2% | 0.24 | 11 / 705 |
blood vessel | 3% | 17.56 | 46 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 3% | 0.33 | 2 / 80 |
heart | 2% | 10.78 | 21 / 861 | 0% | 0 | 0 / 0 |
muscle | 0% | 1.96 | 4 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006915 | Biological process | apoptotic process |
GO_0048870 | Biological process | cell motility |
GO_0007015 | Biological process | actin filament organization |
GO_0006909 | Biological process | phagocytosis |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
GO_0017124 | Molecular function | SH3 domain binding |
Gene name | ELMO3 |
Protein name | Engulfment and cell motility 3 Engulfment and cell motility protein 3 |
Synonyms | |
Description | FUNCTION: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity). . FUNCTION: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. . |
Accessions | ENST00000360833.6 I3L4D1 F8W9E7 ENST00000393997.8 [Q96BJ8-1] ENST00000652269.1 [Q96BJ8-3] Q96BJ8 ENST00000477898.5 [Q96BJ8-2] ENST00000571587.6 |