Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 6 studies | 32% ± 14% | |
| glutamatergic neuron | 4 studies | 31% ± 8% | |
| oligodendrocyte | 4 studies | 21% ± 5% | |
| GABAergic neuron | 3 studies | 29% ± 5% | |
| granule cell | 3 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 28% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 6154.99 | 2642 / 2642 | 100% | 51.69 | 705 / 705 |
| esophagus | 100% | 3754.47 | 1445 / 1445 | 100% | 22.09 | 183 / 183 |
| ovary | 100% | 2793.99 | 180 / 180 | 100% | 26.29 | 430 / 430 |
| prostate | 100% | 4564.81 | 245 / 245 | 100% | 33.99 | 502 / 502 |
| stomach | 100% | 2302.33 | 359 / 359 | 100% | 20.30 | 286 / 286 |
| skin | 100% | 3525.78 | 1808 / 1809 | 100% | 37.50 | 472 / 472 |
| breast | 100% | 3482.51 | 459 / 459 | 100% | 31.88 | 1115 / 1118 |
| lung | 100% | 4555.16 | 578 / 578 | 100% | 20.79 | 1150 / 1155 |
| thymus | 100% | 3593.06 | 653 / 653 | 100% | 28.54 | 602 / 605 |
| intestine | 100% | 3138.65 | 966 / 966 | 99% | 18.20 | 524 / 527 |
| bladder | 100% | 3682.29 | 21 / 21 | 99% | 18.10 | 500 / 504 |
| adrenal gland | 100% | 3445.66 | 258 / 258 | 99% | 25.28 | 227 / 230 |
| uterus | 100% | 4089.36 | 170 / 170 | 99% | 20.37 | 453 / 459 |
| kidney | 100% | 2852.47 | 89 / 89 | 99% | 17.72 | 889 / 901 |
| pancreas | 100% | 2133.73 | 327 / 328 | 99% | 17.29 | 176 / 178 |
| liver | 96% | 1308.90 | 218 / 226 | 77% | 7.52 | 311 / 406 |
| adipose | 100% | 3331.59 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 25.67 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 20.40 | 29 / 29 |
| muscle | 100% | 3100.65 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4970.41 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 15.92 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.31 | 1 / 1 |
| blood vessel | 100% | 3770.54 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 4380.40 | 919 / 929 | 0% | 0 | 0 / 0 |
| heart | 98% | 2157.08 | 846 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006915 | Biological process | apoptotic process |
| GO_0048870 | Biological process | cell motility |
| GO_0060326 | Biological process | cell chemotaxis |
| GO_0007015 | Biological process | actin filament organization |
| GO_0006909 | Biological process | phagocytosis |
| GO_0005829 | Cellular component | cytosol |
| GO_0016020 | Cellular component | membrane |
| GO_0005515 | Molecular function | protein binding |
| GO_0030971 | Molecular function | receptor tyrosine kinase binding |
| GO_0017124 | Molecular function | SH3 domain binding |
| Gene name | ELMO2 |
| Protein name | Engulfment and cell motility 2 (HCG1811050, isoform CRA_b) Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A) Engulfment and cell motility 2 |
| Synonyms | KIAA1834 hCG_1811050 CED12A |
| Description | FUNCTION: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. . FUNCTION: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. . FUNCTION: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. . FUNCTION: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. . |
| Accessions | H0YCM7 ENST00000290246.11 [Q96JJ3-1] ENST00000352077.6 Q5JVZ4 ENST00000452857.5 ENST00000425546.5 ENST00000396391.5 [Q96JJ3-1] Q96JJ3 Q5JVZ5 Q5JVZ8 ENST00000372176.5 [Q96JJ3-3] ENST00000467800.5 Q5JW01 ENST00000450812.5 |
