DYNC1LI2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051642Biological processcentrosome localization
GO_0007018Biological processmicrotubule-based movement
GO_1990090Biological processcellular response to nerve growth factor stimulus
GO_0000226Biological processmicrotubule cytoskeleton organization
GO_0005874Cellular componentmicrotubule
GO_0000776Cellular componentkinetochore
GO_0005813Cellular componentcentrosome
GO_0005829Cellular componentcytosol
GO_0005868Cellular componentcytoplasmic dynein complex
GO_0005770Cellular componentlate endosome
GO_0016020Cellular componentmembrane
GO_0030286Cellular componentdynein complex
GO_0045504Molecular functiondynein heavy chain binding
GO_0042802Molecular functionidentical protein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameDYNC1LI2
Protein nameDynein cytoplasmic 1 light intermediate chain 2
Dynein light intermediate chain
Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55)
SynonymsDNCLI2
LIC2
DescriptionFUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. .

FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. .

FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. .

FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. .

FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. .

AccessionsB4E2E0
J3KRI4
ENST00000564559.6
J3KSD2
ENST00000569320.5
ENST00000440564.6
J3KRZ2
J3QKK5
O43237
ENST00000568180.6
H3BU48
ENST00000258198.7 [O43237-1]
ENST00000566150.5
ENST00000443351.6 [O43237-2]
ENST00000564090.1
ENST00000563628.6
H3BUM4