DYNC1I1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010970Biological processtransport along microtubule
GO_0047496Biological processvesicle transport along microtubule
GO_0005874Cellular componentmicrotubule
GO_0000922Cellular componentspindle pole
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0055037Cellular componentrecycling endosome
GO_0036464Cellular componentcytoplasmic ribonucleoprotein granule
GO_0000776Cellular componentkinetochore
GO_0005868Cellular componentcytoplasmic dynein complex
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0031982Cellular componentvesicle
GO_0005634Cellular componentnucleus
GO_0030507Molecular functionspectrin binding
GO_0045503Molecular functiondynein light chain binding
GO_0003774Molecular functioncytoskeletal motor activity
GO_0003777Molecular functionmicrotubule motor activity
GO_0008017Molecular functionmicrotubule binding
GO_0005515Molecular functionprotein binding
GO_0045504Molecular functiondynein heavy chain binding

IV. Literature review

[source]
Gene nameDYNC1I1
Protein nameCytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1)
Dynein, cytoplasmic 1, intermediate chain 1, isoform CRA_e (Dynein, cytoplasmic, intermediate polypeptide 1)
Dynein cytoplasmic 1 intermediate chain 1
DYNC1I1 protein
SynonymshCG_40542
DNCIC1
tcag7.305
DNCI1
DescriptionFUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

AccessionsENST00000524053.5
ENST00000457059.2 [O14576-2]
Q8IY52
ENST00000359388.8 [O14576-3]
ENST00000413338.5
Q8N542
ENST00000537881.5
ENST00000324972.10 [O14576-1]
ENST00000437599.5 [O14576-5]
C9J3E7
ENST00000518089.5
E5RFE1
A4D1I7
ENST00000630942.2 [O14576-4]
ENST00000447467.6 [O14576-2]
E5RJ75
O14576
Q7Z6M0
A0A0A0MTG2