Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 13 studies | 35% ± 15% | |
glutamatergic neuron | 12 studies | 69% ± 21% | |
GABAergic neuron | 10 studies | 57% ± 29% | |
astrocyte | 8 studies | 47% ± 21% | |
oligodendrocyte precursor cell | 8 studies | 28% ± 13% | |
neuron | 6 studies | 40% ± 22% | |
endothelial cell | 6 studies | 43% ± 14% | |
interneuron | 6 studies | 55% ± 33% | |
retinal ganglion cell | 6 studies | 72% ± 24% | |
endothelial cell of lymphatic vessel | 6 studies | 30% ± 8% | |
cardiac muscle cell | 5 studies | 46% ± 13% | |
Mueller cell | 5 studies | 57% ± 16% | |
microglial cell | 4 studies | 30% ± 16% | |
fibroblast | 4 studies | 32% ± 16% | |
retinal cone cell | 4 studies | 31% ± 11% | |
OFF-bipolar cell | 4 studies | 44% ± 25% | |
smooth muscle cell | 4 studies | 29% ± 8% | |
GABAergic interneuron | 3 studies | 50% ± 21% | |
retinal pigment epithelial cell | 3 studies | 61% ± 19% | |
pericyte | 3 studies | 34% ± 9% | |
granule cell | 3 studies | 68% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 5255.91 | 2609 / 2642 | 95% | 21.77 | 670 / 705 |
prostate | 77% | 700.06 | 189 / 245 | 77% | 4.01 | 385 / 502 |
adrenal gland | 25% | 247.95 | 64 / 258 | 92% | 49.94 | 211 / 230 |
bladder | 67% | 2449.71 | 14 / 21 | 49% | 3.92 | 246 / 504 |
esophagus | 57% | 515.34 | 817 / 1445 | 51% | 3.77 | 94 / 183 |
ovary | 84% | 639.16 | 152 / 180 | 19% | 0.82 | 83 / 430 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.36 | 1 / 1 |
blood vessel | 91% | 1028.12 | 1220 / 1335 | 0% | 0 | 0 / 0 |
thymus | 55% | 305.36 | 359 / 653 | 35% | 2.21 | 211 / 605 |
skin | 18% | 97.37 | 324 / 1809 | 71% | 8.72 | 336 / 472 |
heart | 88% | 1329.31 | 759 / 861 | 0% | 0 | 0 / 0 |
intestine | 67% | 1424.42 | 652 / 966 | 17% | 0.84 | 87 / 527 |
muscle | 69% | 690.29 | 558 / 803 | 0% | 0 | 0 / 0 |
pancreas | 0% | 1.61 | 1 / 328 | 69% | 4.77 | 123 / 178 |
kidney | 19% | 92.83 | 17 / 89 | 45% | 2.14 | 409 / 901 |
breast | 39% | 239.29 | 178 / 459 | 22% | 1.28 | 247 / 1118 |
uterus | 25% | 130.15 | 42 / 170 | 32% | 3.39 | 146 / 459 |
stomach | 34% | 633.59 | 122 / 359 | 22% | 1.28 | 64 / 286 |
lung | 1% | 5.67 | 5 / 578 | 51% | 5.15 | 586 / 1155 |
eye | 0% | 0 | 0 / 0 | 48% | 4.56 | 38 / 80 |
adipose | 29% | 163.19 | 350 / 1204 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 25% | 3.44 | 101 / 406 |
tonsil | 0% | 0 | 0 / 0 | 13% | 0.90 | 6 / 45 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.29 | 2 / 29 |
peripheral blood | 0% | 0.78 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
GO_0010970 | Biological process | transport along microtubule |
GO_0047496 | Biological process | vesicle transport along microtubule |
GO_0005874 | Cellular component | microtubule |
GO_0000922 | Cellular component | spindle pole |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0055037 | Cellular component | recycling endosome |
GO_0036464 | Cellular component | cytoplasmic ribonucleoprotein granule |
GO_0000776 | Cellular component | kinetochore |
GO_0005868 | Cellular component | cytoplasmic dynein complex |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0031982 | Cellular component | vesicle |
GO_0005634 | Cellular component | nucleus |
GO_0030507 | Molecular function | spectrin binding |
GO_0045503 | Molecular function | dynein light chain binding |
GO_0003774 | Molecular function | cytoskeletal motor activity |
GO_0003777 | Molecular function | microtubule motor activity |
GO_0008017 | Molecular function | microtubule binding |
GO_0005515 | Molecular function | protein binding |
GO_0045504 | Molecular function | dynein heavy chain binding |
Gene name | DYNC1I1 |
Protein name | Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1) Dynein, cytoplasmic 1, intermediate chain 1, isoform CRA_e (Dynein, cytoplasmic, intermediate polypeptide 1) Dynein cytoplasmic 1 intermediate chain 1 DYNC1I1 protein |
Synonyms | hCG_40542 DNCIC1 tcag7.305 DNCI1 |
Description | FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores. |
Accessions | ENST00000524053.5 ENST00000457059.2 [O14576-2] Q8IY52 ENST00000359388.8 [O14576-3] ENST00000413338.5 Q8N542 ENST00000537881.5 ENST00000324972.10 [O14576-1] ENST00000437599.5 [O14576-5] C9J3E7 ENST00000518089.5 E5RFE1 A4D1I7 ENST00000630942.2 [O14576-4] ENST00000447467.6 [O14576-2] E5RJ75 O14576 Q7Z6M0 A0A0A0MTG2 |