DUSP15 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DUSP15 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DUSP15 at tissue level.

III. Associated gene sets

GO_0048713Biological processregulation of oligodendrocyte differentiation
GO_0007165Biological processsignal transduction
GO_0016311Biological processdephosphorylation
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0016791Molecular functionphosphatase activity
GO_0008138Molecular functionprotein tyrosine/serine/threonine phosphatase activity
GO_0017018Molecular functionmyosin phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene nameDUSP15
Protein nameDual specificity protein phosphatase 15 (EC 3.1.3.16) (EC 3.1.3.48) (VH1-related member Y) (Vaccinia virus VH1-related dual-specific protein phosphatase Y)
Dual specificity phosphatase 15
SynonymsC20orf57
VHY
DescriptionFUNCTION: May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6 . .; FUNCTION: [Isoform 3]: May play a role in the regulation of oligodendrocyte differentiation. May play a role in the regulation of myelin formation (By similarity). Involved in the regulation of Erk1/2 phosphorylation in Schwann cells; the signaling may be linked to the regulation of myelination (By similarity). .

AccessionsH0Y5A2
ENST00000398083.5 [Q9H1R2-4]
ENST00000447647.5
ENST00000428829.1
ENST00000339738.10 [Q9H1R2-3]
Q5QP64
ENST00000486996.5 [Q9H1R2-4]
Q9H1R2
ENST00000375966.8 [Q9H1R2-2]
ENST00000398084.6 [Q9H1R2-4]
ENST00000278979.7 [Q9H1R2-1]