DUSP14 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0017017Molecular functionMAP kinase tyrosine/serine/threonine phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0017018Molecular functionmyosin phosphatase activity
GO_0003723Molecular functionRNA binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene nameDUSP14
Protein nameDUSP14 protein (Dual specificity phosphatase 14, isoform CRA_a) (cDNA, FLJ95796, Homo sapiens dual specificity phosphatase 14 (DUSP14), mRNA)
Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48) (MKP-1-like protein tyrosine phosphatase) (MKP-L) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6)
SynonymshCG_28185
MKP6
DescriptionFUNCTION: Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases. Plays a negative role in TCR signaling by dephosphorylating MAP3K7 adapter TAB1 leading to its inactivation . .

AccessionsENST00000614294.2
ENST00000617516.5
O95147
ENST00000632468.1
ENST00000633870.1
ENST00000614411.1
ENST00000613659.1
Q6FI36