DUSP12 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DUSP12 at tissue level.

III. Associated gene sets

GO_0006470Biological processprotein dephosphorylation
GO_0036211Biological processprotein modification process
GO_0016311Biological processdephosphorylation
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0019900Molecular functionkinase binding
GO_0016791Molecular functionphosphatase activity
GO_0008138Molecular functionprotein tyrosine/serine/threonine phosphatase activity
GO_0004725Molecular functionprotein tyrosine phosphatase activity
GO_0017018Molecular functionmyosin phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameDUSP12
Protein nameDual specificity phosphatase 12
Dual specificity protein phosphatase 12 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity tyrosine phosphatase YVH1)
Synonyms
DescriptionFUNCTION: Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. Can dephosphorylate glucokinase (in vitro) (By similarity). Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate and other in vitro substrates . .

AccessionsENST00000367943.5
ENST00000484291.5
V9GY92
Q9UNI6
ENST00000490591.1
ENST00000464004.2
V9GYV5