DUS3L report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DUS3L at tissue level.

III. Associated gene sets

GO_0002943Biological processtRNA dihydrouridine synthesis
GO_0006397Biological processmRNA processing
GO_0006417Biological processregulation of translation
GO_0017150Molecular functiontRNA dihydrouridine synthase activity
GO_0050660Molecular functionflavin adenine dinucleotide binding
GO_0005515Molecular functionprotein binding
GO_0106414Molecular functionmRNA dihydrouridine synthase activity
GO_0046872Molecular functionmetal ion binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameDUS3L
Protein nameDihydrouridine synthase 3 like
tRNA-dihydrouridine(47) synthase [NAD(P)(+)] (EC 1.3.1.89)
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.89) (mRNA-dihydrouridine synthase DUS3L) (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like)
Synonyms
DescriptionFUNCTION: Catalyzes the synthesis of dihydrouridine, a modified base, in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs) . Mainly modifies the uridine in position 47 (U47) in the D-loop of most cytoplasmic tRNAs . Also able to mediate the formation of dihydrouridine in some mRNAs, thereby regulating their translation . .

AccessionsK7ERF2
ENST00000592491.1
Q96G46
ENST00000592468.5
K7EQU9
ENST00000591560.5
K7EJX8
ENST00000309061.12 [Q96G46-1]
K7EM42
ENST00000590343.1
ENST00000320699.12 [Q96G46-3]
K7ER20
K7EPA4
ENST00000585587.1
ENST00000590110.2