DPT report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DPT at tissue level.

III. Associated gene sets

GO_0008285Biological processnegative regulation of cell population proliferation
GO_0030199Biological processcollagen fibril organization
GO_0007155Biological processcell adhesion
GO_0005615Cellular componentextracellular space
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0005201Molecular functionextracellular matrix structural constituent
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDPT
Protein nameAlternative protein DPT
Dermatopontin (Tyrosine-rich acidic matrix protein) (TRAMP)
Synonyms
DescriptionFUNCTION: Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity). .

AccessionsL8E7N7
ENST00000367817.4
Q07507