DNAL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0036158Biological processouter dynein arm assembly
GO_0036157Cellular componentouter dynein arm
GO_0005874Cellular componentmicrotubule
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0043014Molecular functionalpha-tubulin binding
GO_0045504Molecular functiondynein heavy chain binding

IV. Literature review

[source]
Gene nameDNAL1
Protein nameDynein axonemal light chain 1
Dynein axonemal light chain 1 (LC1)
SynonymsC14orf168
DescriptionFUNCTION: Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry . .

AccessionsENST00000554113.5
ENST00000554339.5
ENST00000311089.7 [Q4LDG9-2]
ENST00000554159.1
ENST00000555919.7
G3V389
ENST00000553645.7 [Q4LDG9-1]
G3V424
ENST00000555631.6
H0YJD6
H0YM28
ENST00000559993.1
G3V5I4
G3V2M0
Q4LDG9
ENST00000554871.5 [Q4LDG9-3]