I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 32% ± 5% | |
| glutamatergic neuron | 3 studies | 39% ± 9% | |
| pericyte | 3 studies | 18% ± 1% | |
| astrocyte | 3 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 32% ± 5% | |
| glutamatergic neuron | 3 studies | 39% ± 9% | |
| pericyte | 3 studies | 18% ± 1% | |
| astrocyte | 3 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 27% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 1184.80 | 2641 / 2642 | 100% | 7.01 | 705 / 705 |
| esophagus | 100% | 683.24 | 1440 / 1445 | 100% | 4.48 | 183 / 183 |
| thymus | 100% | 902.94 | 653 / 653 | 99% | 4.76 | 600 / 605 |
| breast | 100% | 923.98 | 459 / 459 | 99% | 5.01 | 1108 / 1118 |
| prostate | 100% | 821.75 | 245 / 245 | 99% | 4.22 | 497 / 502 |
| kidney | 100% | 669.71 | 89 / 89 | 98% | 5.32 | 887 / 901 |
| lung | 99% | 645.03 | 574 / 578 | 99% | 3.84 | 1143 / 1155 |
| ovary | 100% | 1675.52 | 180 / 180 | 98% | 3.54 | 422 / 430 |
| stomach | 100% | 599.90 | 359 / 359 | 97% | 2.90 | 278 / 286 |
| uterus | 100% | 997.08 | 170 / 170 | 97% | 3.30 | 446 / 459 |
| adrenal gland | 100% | 664.67 | 258 / 258 | 97% | 5.59 | 223 / 230 |
| bladder | 100% | 788.38 | 21 / 21 | 95% | 2.92 | 480 / 504 |
| intestine | 100% | 808.92 | 966 / 966 | 95% | 2.62 | 501 / 527 |
| pancreas | 98% | 389.67 | 320 / 328 | 97% | 3.24 | 173 / 178 |
| skin | 100% | 584.32 | 1805 / 1809 | 91% | 3.11 | 430 / 472 |
| liver | 89% | 250.93 | 202 / 226 | 55% | 1.14 | 225 / 406 |
| adipose | 100% | 1080.73 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 715.28 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 727.04 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 2.94 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.39 | 1 / 1 |
| muscle | 100% | 636.88 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 718.01 | 838 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 86% | 2.47 | 25 / 29 |
| eye | 0% | 0 | 0 / 0 | 80% | 3.03 | 64 / 80 |
| peripheral blood | 46% | 203.67 | 428 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006886 | Biological process | intracellular protein transport |
| GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
| GO_0005634 | Cellular component | nucleus |
| GO_0005525 | Molecular function | GTP binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | DNAJC27 |
| Protein name | DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein) |
| Synonyms | RABJS RBJ |
| Description | FUNCTION: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. . |
| Accessions | ENST00000534855.5 [Q9NZQ0-3] ENST00000264711.7 [Q9NZQ0-1] Q9NZQ0 ENST00000380809.7 [Q9NZQ0-2] |
