Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 15 studies | 36% ± 13% | |
retinal rod cell | 3 studies | 25% ± 6% |
Insufficient scRNA-seq data for expression of DNAH2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 97% | 967.81 | 175 / 180 | 49% | 1.47 | 211 / 430 |
lung | 88% | 795.74 | 510 / 578 | 57% | 2.83 | 658 / 1155 |
breast | 95% | 223.47 | 438 / 459 | 39% | 0.94 | 432 / 1118 |
uterus | 92% | 311.62 | 156 / 170 | 33% | 1.01 | 152 / 459 |
pancreas | 44% | 48.03 | 145 / 328 | 55% | 2.06 | 98 / 178 |
brain | 92% | 620.11 | 2428 / 2642 | 6% | 0.20 | 43 / 705 |
prostate | 90% | 143.97 | 220 / 245 | 7% | 0.12 | 33 / 502 |
adipose | 82% | 123.85 | 990 / 1204 | 0% | 0 | 0 / 0 |
bladder | 52% | 76.71 | 11 / 21 | 23% | 0.79 | 116 / 504 |
liver | 72% | 89.05 | 162 / 226 | 3% | 0.06 | 12 / 406 |
thymus | 66% | 70.44 | 431 / 653 | 6% | 0.17 | 38 / 605 |
intestine | 39% | 33.93 | 378 / 966 | 33% | 0.91 | 172 / 527 |
skin | 25% | 23.31 | 452 / 1809 | 41% | 1.88 | 192 / 472 |
esophagus | 21% | 19.87 | 304 / 1445 | 36% | 1.64 | 65 / 183 |
kidney | 46% | 41.47 | 41 / 89 | 7% | 0.15 | 67 / 901 |
stomach | 18% | 15.30 | 64 / 359 | 26% | 0.62 | 75 / 286 |
spleen | 25% | 24.10 | 60 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 22% | 0.49 | 10 / 45 |
blood vessel | 17% | 15.53 | 224 / 1335 | 0% | 0 | 0 / 0 |
heart | 11% | 10.06 | 94 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 8% | 6.49 | 20 / 258 | 2% | 0.06 | 5 / 230 |
eye | 0% | 0 | 0 / 0 | 8% | 0.18 | 6 / 80 |
muscle | 5% | 3.92 | 38 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 2.49 | 8 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0060294 | Biological process | cilium movement involved in cell motility |
GO_0036159 | Biological process | inner dynein arm assembly |
GO_0060285 | Biological process | cilium-dependent cell motility |
GO_0036156 | Cellular component | inner dynein arm |
GO_0005930 | Cellular component | axoneme |
GO_0005874 | Cellular component | microtubule |
GO_0031514 | Cellular component | motile cilium |
GO_0005858 | Cellular component | axonemal dynein complex |
GO_0036126 | Cellular component | sperm flagellum |
GO_0097729 | Cellular component | 9+2 motile cilium |
GO_0030286 | Cellular component | dynein complex |
GO_0051959 | Molecular function | dynein light intermediate chain binding |
GO_0008569 | Molecular function | minus-end-directed microtubule motor activity |
GO_0045505 | Molecular function | dynein intermediate chain binding |
GO_0003777 | Molecular function | microtubule motor activity |
GO_0016887 | Molecular function | ATP hydrolysis activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | DNAH2 |
Protein name | Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) (Dynein heavy chain domain-containing protein 3) Alternative protein DNAH2 Dynein axonemal heavy chain 2 |
Synonyms | DNHD3 DNAHC2 KIAA1503 |
Description | FUNCTION: As part of the axonemal inner dynein arm complex plays a central role in ciliary beat . Expressed in sperm flagellum, it is required for sperm motility . Dyneins are microtubule-based molecular motors possessing ATPase activities that can convert the chemical energy of ATP into relative sliding between adjacent microtubule doublets to generate ciliary bending . . |
Accessions | ENST00000570791.5 [Q9P225-3] I3L4H9 Q9P225 ENST00000572933.6 [Q9P225-1] ENST00000389173.6 [Q9P225-1] L8E8M4 I3L520 ENST00000575105.1 ENST00000574518.1 |