DNAH2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DNAH2 at tissue level.

III. Associated gene sets

GO_0060294Biological processcilium movement involved in cell motility
GO_0036159Biological processinner dynein arm assembly
GO_0060285Biological processcilium-dependent cell motility
GO_0036156Cellular componentinner dynein arm
GO_0005930Cellular componentaxoneme
GO_0005874Cellular componentmicrotubule
GO_0031514Cellular componentmotile cilium
GO_0005858Cellular componentaxonemal dynein complex
GO_0036126Cellular componentsperm flagellum
GO_0097729Cellular component9+2 motile cilium
GO_0030286Cellular componentdynein complex
GO_0051959Molecular functiondynein light intermediate chain binding
GO_0008569Molecular functionminus-end-directed microtubule motor activity
GO_0045505Molecular functiondynein intermediate chain binding
GO_0003777Molecular functionmicrotubule motor activity
GO_0016887Molecular functionATP hydrolysis activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameDNAH2
Protein nameDynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) (Dynein heavy chain domain-containing protein 3)
Alternative protein DNAH2
Dynein axonemal heavy chain 2
SynonymsDNHD3
DNAHC2
KIAA1503
DescriptionFUNCTION: As part of the axonemal inner dynein arm complex plays a central role in ciliary beat . Expressed in sperm flagellum, it is required for sperm motility . Dyneins are microtubule-based molecular motors possessing ATPase activities that can convert the chemical energy of ATP into relative sliding between adjacent microtubule doublets to generate ciliary bending . .

AccessionsENST00000570791.5 [Q9P225-3]
I3L4H9
Q9P225
ENST00000572933.6 [Q9P225-1]
ENST00000389173.6 [Q9P225-1]
L8E8M4
I3L520
ENST00000575105.1
ENST00000574518.1