I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 24% ± 6% | |
| adipocyte | 4 studies | 27% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 24% ± 6% | |
| adipocyte | 4 studies | 27% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 26% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 100% | 2285.22 | 966 / 966 | 100% | 35.61 | 527 / 527 |
| esophagus | 100% | 2155.95 | 1444 / 1445 | 100% | 31.72 | 183 / 183 |
| stomach | 100% | 1619.89 | 358 / 359 | 100% | 35.90 | 286 / 286 |
| ovary | 99% | 1227.87 | 179 / 180 | 100% | 29.15 | 430 / 430 |
| breast | 100% | 2583.47 | 459 / 459 | 99% | 31.24 | 1104 / 1118 |
| brain | 99% | 1841.08 | 2605 / 2642 | 99% | 27.11 | 701 / 705 |
| bladder | 100% | 1869.48 | 21 / 21 | 98% | 26.44 | 492 / 504 |
| skin | 100% | 2252.91 | 1807 / 1809 | 97% | 28.45 | 459 / 472 |
| kidney | 100% | 2437.33 | 89 / 89 | 97% | 30.97 | 875 / 901 |
| thymus | 100% | 1963.07 | 651 / 653 | 97% | 26.10 | 589 / 605 |
| lung | 97% | 1605.05 | 560 / 578 | 100% | 32.54 | 1154 / 1155 |
| prostate | 100% | 1389.47 | 244 / 245 | 97% | 22.96 | 485 / 502 |
| uterus | 99% | 1395.41 | 169 / 170 | 96% | 21.80 | 441 / 459 |
| adrenal gland | 100% | 2325.76 | 258 / 258 | 89% | 19.77 | 204 / 230 |
| pancreas | 89% | 734.47 | 291 / 328 | 98% | 19.17 | 175 / 178 |
| liver | 96% | 1164.23 | 216 / 226 | 90% | 16.78 | 365 / 406 |
| adipose | 100% | 2982.30 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 25.97 | 29 / 29 |
| muscle | 100% | 5604.01 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1197.98 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 6.85 | 1 / 1 |
| blood vessel | 100% | 1617.19 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| heart | 97% | 5347.58 | 832 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 94% | 18.07 | 75 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 18.62 | 42 / 45 |
| peripheral blood | 32% | 1006.33 | 295 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006086 | Biological process | acetyl-CoA biosynthetic process from pyruvate |
| GO_0006099 | Biological process | tricarboxylic acid cycle |
| GO_0006006 | Biological process | glucose metabolic process |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0045254 | Cellular component | pyruvate dehydrogenase complex |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0034604 | Molecular function | pyruvate dehydrogenase (NAD+) activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0004742 | Molecular function | dihydrolipoyllysine-residue acetyltransferase activity |
| Gene name | DLAT |
| Protein name | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-) Dihydrolipoamide S-acetyltransferase Acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (M2 antigen complex 70 kDa subunit) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) |
| Synonyms | DLTA |
| Description | FUNCTION: As part of the pyruvate dehydrogenase complex, catalyzes the transfers of an acetyl group to a lipoic acid moiety (Probable). The pyruvate dehydrogenase complex, catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links cytoplasmic glycolysis and the mitochondrial tricarboxylic acid (TCA) cycle (Probable). . FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). . FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). . FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). . FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). . FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). . FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). . FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). . FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). . FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). . |
| Accessions | ENST00000280346.11 ENST00000679614.1 ENST00000681638.1 H0YDD4 ENST00000681328.1 ENST00000680411.1 A0A7P0TAX2 ENST00000393051.5 A0A7P0Z459 ENST00000681316.1 ENST00000679368.1 A0A7P0Z423 ENST00000533297.1 A0A7P0T997 A0A7P0T9N8 Q86YI5 P10515 E9PKC7 A0A7P0TAG1 ENST00000680010.1 ENST00000679815.1 E9PEJ4 A0A7P0TBE2 ENST00000679878.1 ENST00000531306.2 A0A7P0Z4G4 ENST00000680331.1 A0A7P0TBK2 A0A7P0TA47 ENST00000681339.1 |
