DFFA report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006309Biological processapoptotic DNA fragmentation
GO_0043065Biological processpositive regulation of apoptotic process
GO_0061077Biological processchaperone-mediated protein folding
GO_0032076Biological processnegative regulation of deoxyribonuclease activity
GO_0070242Biological processthymocyte apoptotic process
GO_1900118Biological processnegative regulation of execution phase of apoptosis
GO_1902511Biological processnegative regulation of apoptotic DNA fragmentation
GO_0032991Cellular componentprotein-containing complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0005886Cellular componentplasma membrane
GO_0005634Cellular componentnucleus
GO_0044183Molecular functionprotein folding chaperone
GO_0060703Molecular functiondeoxyribonuclease inhibitor activity
GO_0019904Molecular functionprotein domain specific binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDFFA
Protein nameDNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD)
DNA fragmentation factor subunit alpha
SynonymsDFF45
H13
DFF1
DescriptionFUNCTION: Inhibitor of the caspase-activated DNase (DFF40).

AccessionsENST00000476658.5
ENST00000377036.2 [O00273-2]
K7ERT1
ENST00000377038.8 [O00273-1]
O00273