Name | Number of supported studies | Average coverage | |
---|---|---|---|
type II pneumocyte | 11 studies | 26% ± 10% | |
type I pneumocyte | 10 studies | 27% ± 8% | |
endothelial cell | 10 studies | 25% ± 7% | |
fibroblast | 9 studies | 21% ± 5% | |
epithelial cell | 8 studies | 27% ± 9% | |
ciliated cell | 6 studies | 26% ± 5% | |
myofibroblast cell | 4 studies | 20% ± 1% | |
macrophage | 4 studies | 19% ± 3% | |
microglial cell | 3 studies | 19% ± 3% | |
precursor B cell | 3 studies | 21% ± 4% | |
GABAergic neuron | 3 studies | 33% ± 3% | |
glutamatergic neuron | 3 studies | 36% ± 6% | |
oligodendrocyte precursor cell | 3 studies | 27% ± 6% | |
basal cell | 3 studies | 27% ± 6% | |
transit amplifying cell | 3 studies | 24% ± 10% | |
astrocyte | 3 studies | 25% ± 5% | |
oligodendrocyte | 3 studies | 18% ± 0% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2537.16 | 1445 / 1445 | 100% | 54.72 | 183 / 183 |
lung | 100% | 3886.65 | 578 / 578 | 100% | 55.47 | 1155 / 1155 |
ovary | 100% | 2118.10 | 180 / 180 | 100% | 41.54 | 429 / 430 |
breast | 100% | 2203.62 | 459 / 459 | 100% | 54.73 | 1115 / 1118 |
intestine | 100% | 2708.63 | 966 / 966 | 100% | 40.41 | 525 / 527 |
uterus | 100% | 3322.72 | 170 / 170 | 100% | 52.58 | 457 / 459 |
bladder | 100% | 2816.10 | 21 / 21 | 99% | 40.19 | 501 / 504 |
stomach | 100% | 2371.47 | 359 / 359 | 99% | 40.63 | 284 / 286 |
thymus | 100% | 3401.11 | 653 / 653 | 99% | 35.72 | 600 / 605 |
prostate | 100% | 2277.71 | 245 / 245 | 98% | 23.72 | 490 / 502 |
skin | 100% | 2949.15 | 1809 / 1809 | 97% | 44.59 | 456 / 472 |
pancreas | 98% | 1028.15 | 320 / 328 | 99% | 35.52 | 176 / 178 |
brain | 96% | 1288.74 | 2548 / 2642 | 99% | 28.41 | 698 / 705 |
kidney | 100% | 1475.30 | 89 / 89 | 95% | 25.67 | 856 / 901 |
adrenal gland | 100% | 2400.02 | 258 / 258 | 91% | 18.89 | 210 / 230 |
liver | 100% | 1127.95 | 226 / 226 | 89% | 20.30 | 360 / 406 |
adipose | 100% | 2669.12 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3865.80 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 32.21 | 29 / 29 |
muscle | 100% | 1913.82 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1799.80 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 47.30 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 27.04 | 1 / 1 |
heart | 99% | 1776.11 | 853 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 86% | 15.46 | 69 / 80 |
peripheral blood | 64% | 732.76 | 594 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0098734 | Biological process | macromolecule depalmitoylation |
GO_0016579 | Biological process | protein deubiquitination |
GO_0006508 | Biological process | proteolysis |
GO_0005737 | Cellular component | cytoplasm |
GO_0052816 | Molecular function | long-chain fatty acyl-CoA hydrolase activity |
GO_0101005 | Molecular function | deubiquitinase activity |
GO_0005515 | Molecular function | protein binding |
GO_0004843 | Molecular function | cysteine-type deubiquitinase activity |
GO_1990380 | Molecular function | K48-linked deubiquitinase activity |
GO_0061578 | Molecular function | K63-linked deubiquitinase activity |
GO_0008474 | Molecular function | palmitoyl-(protein) hydrolase activity |
Gene name | DESI2 |
Protein name | Deubiquitinase DESI2 (EC 3.4.19.12) (Desumoylating isopeptidase 2) (PPPDE peptidase domain-containing protein 1) (Protein FAM152A) Deubiquitinase DESI2 (EC 3.4.19.12) (Desumoylating isopeptidase 2) (DeSI-2) (PPPDE peptidase domain-containing protein 1) (Palmitoyl protein thioesterase DESI2) (EC 3.1.2.22) (Protein FAM152A) (S-depalmitoylase DESI2) |
Synonyms | PPPDE1 FAM152A CGI-146 PNAS-4 C1orf121 |
Description | FUNCTION: Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization . Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity towards synthetic substrates 4-methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S-depalmitoylation probe 5 (DPP-5) . . |
Accessions | B1APK7 ENST00000418162.1 ENST00000302550.16 [Q9BSY9-1] ENST00000263831.11 [Q9BSY9-2] Q9BSY9 |