DENND6A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2000049Biological processpositive regulation of cell-cell adhesion mediated by cadherin
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0055037Cellular componentrecycling endosome
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity

IV. Literature review

[source]
Gene nameDENND6A
Protein nameDENN domain containing 6A
Protein DENND6A (DENN domain-containing protein 6A)
SynonymsFAM116A
DescriptionFUNCTION: Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes. .

AccessionsENST00000311128.10
ENST00000477344.1
Q8IWF6
H7C5D0
ENST00000471531.1
H7C598