Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 14 studies | 25% ± 8% | |
microglial cell | 8 studies | 25% ± 7% | |
GABAergic neuron | 7 studies | 36% ± 20% | |
oligodendrocyte | 7 studies | 29% ± 6% | |
glutamatergic neuron | 6 studies | 46% ± 24% | |
fibroblast | 6 studies | 29% ± 11% | |
astrocyte | 6 studies | 30% ± 9% | |
macrophage | 5 studies | 31% ± 9% | |
interneuron | 5 studies | 37% ± 23% | |
cardiac muscle cell | 4 studies | 18% ± 3% | |
dendritic cell | 4 studies | 17% ± 2% | |
oligodendrocyte precursor cell | 4 studies | 29% ± 8% | |
T cell | 4 studies | 19% ± 4% | |
endothelial cell of lymphatic vessel | 4 studies | 27% ± 6% | |
pericyte | 4 studies | 27% ± 8% | |
smooth muscle cell | 4 studies | 23% ± 2% | |
type I pneumocyte | 4 studies | 21% ± 5% | |
myeloid cell | 3 studies | 20% ± 1% | |
epithelial cell | 3 studies | 37% ± 16% | |
CD4-positive, alpha-beta T cell | 3 studies | 20% ± 2% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 22% ± 4% | |
monocyte | 3 studies | 24% ± 5% | |
natural killer cell | 3 studies | 21% ± 4% | |
lymphocyte | 3 studies | 32% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 2426.29 | 21 / 21 | 100% | 18.22 | 504 / 504 |
lung | 100% | 2136.06 | 578 / 578 | 100% | 17.36 | 1155 / 1155 |
ovary | 100% | 2855.43 | 180 / 180 | 100% | 13.70 | 430 / 430 |
prostate | 100% | 1979.64 | 245 / 245 | 100% | 16.24 | 502 / 502 |
uterus | 100% | 2612.39 | 170 / 170 | 100% | 20.73 | 459 / 459 |
breast | 100% | 2498.19 | 459 / 459 | 100% | 25.58 | 1117 / 1118 |
thymus | 100% | 2435.44 | 653 / 653 | 100% | 17.99 | 603 / 605 |
intestine | 100% | 2139.58 | 966 / 966 | 100% | 15.21 | 525 / 527 |
kidney | 100% | 1355.53 | 89 / 89 | 100% | 17.05 | 897 / 901 |
esophagus | 100% | 2145.70 | 1445 / 1445 | 99% | 21.09 | 182 / 183 |
stomach | 100% | 1475.80 | 359 / 359 | 99% | 16.00 | 283 / 286 |
brain | 99% | 1078.28 | 2611 / 2642 | 100% | 17.45 | 705 / 705 |
adrenal gland | 100% | 1486.75 | 258 / 258 | 98% | 11.66 | 225 / 230 |
skin | 100% | 1630.69 | 1809 / 1809 | 98% | 19.56 | 461 / 472 |
liver | 99% | 655.46 | 224 / 226 | 96% | 8.15 | 389 / 406 |
pancreas | 95% | 666.18 | 311 / 328 | 99% | 18.13 | 176 / 178 |
adipose | 100% | 2450.11 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2291.27 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 13.18 | 29 / 29 |
spleen | 100% | 2441.97 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 22.70 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.23 | 1 / 1 |
heart | 99% | 988.23 | 852 / 861 | 0% | 0 | 0 / 0 |
muscle | 99% | 928.35 | 791 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 91% | 992.66 | 849 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 83% | 7.57 | 66 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_2000049 | Biological process | positive regulation of cell-cell adhesion mediated by cadherin |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0055037 | Cellular component | recycling endosome |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
Gene name | DENND6A |
Protein name | DENN domain containing 6A Protein DENND6A (DENN domain-containing protein 6A) |
Synonyms | FAM116A |
Description | FUNCTION: Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes. . |
Accessions | ENST00000311128.10 ENST00000477344.1 Q8IWF6 H7C5D0 ENST00000471531.1 H7C598 |