Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 17 studies | 26% ± 10% | |
non-classical monocyte | 17 studies | 31% ± 11% | |
monocyte | 9 studies | 22% ± 4% | |
epithelial cell | 6 studies | 29% ± 10% | |
macrophage | 4 studies | 21% ± 6% | |
glutamatergic neuron | 4 studies | 36% ± 13% | |
squamous epithelial cell | 3 studies | 31% ± 22% | |
hematopoietic precursor cell | 3 studies | 25% ± 7% | |
endothelial cell | 3 studies | 21% ± 5% | |
erythroblast | 3 studies | 28% ± 4% | |
fibroblast | 3 studies | 22% ± 3% | |
ciliated cell | 3 studies | 29% ± 7% | |
GABAergic neuron | 3 studies | 35% ± 3% | |
astrocyte | 3 studies | 20% ± 2% | |
dendritic cell | 3 studies | 26% ± 11% | |
basal cell | 3 studies | 31% ± 12% | |
oligodendrocyte | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1118.43 | 2642 / 2642 | 100% | 8.89 | 705 / 705 |
esophagus | 100% | 892.22 | 1445 / 1445 | 100% | 8.51 | 183 / 183 |
ovary | 100% | 1096.44 | 180 / 180 | 100% | 9.01 | 430 / 430 |
breast | 100% | 934.25 | 459 / 459 | 100% | 8.67 | 1116 / 1118 |
lung | 100% | 812.12 | 576 / 578 | 100% | 8.80 | 1155 / 1155 |
stomach | 100% | 591.83 | 359 / 359 | 100% | 6.95 | 285 / 286 |
prostate | 100% | 925.36 | 245 / 245 | 100% | 8.22 | 500 / 502 |
thymus | 100% | 965.49 | 653 / 653 | 99% | 8.34 | 601 / 605 |
bladder | 100% | 872.24 | 21 / 21 | 99% | 7.00 | 500 / 504 |
uterus | 100% | 907.99 | 170 / 170 | 99% | 7.29 | 455 / 459 |
intestine | 100% | 920.37 | 966 / 966 | 99% | 6.52 | 522 / 527 |
liver | 100% | 775.11 | 226 / 226 | 99% | 8.34 | 402 / 406 |
kidney | 100% | 1072.36 | 89 / 89 | 99% | 6.86 | 892 / 901 |
pancreas | 99% | 427.40 | 326 / 328 | 99% | 6.03 | 176 / 178 |
skin | 100% | 1288.87 | 1809 / 1809 | 98% | 8.16 | 461 / 472 |
adrenal gland | 100% | 1039.55 | 258 / 258 | 94% | 4.99 | 216 / 230 |
adipose | 100% | 1044.52 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1045.46 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 6.38 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.43 | 1 / 1 |
muscle | 100% | 692.68 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 563.06 | 1328 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 1141.91 | 911 / 929 | 0% | 0 | 0 / 0 |
heart | 98% | 561.32 | 843 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 5.72 | 28 / 29 |
eye | 0% | 0 | 0 / 0 | 95% | 7.10 | 76 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_2000641 | Biological process | regulation of early endosome to late endosome transport |
GO_0015031 | Biological process | protein transport |
GO_0032509 | Biological process | endosome transport via multivesicular body sorting pathway |
GO_0005770 | Cellular component | late endosome |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0031267 | Molecular function | small GTPase binding |
Gene name | DENND10 |
Protein name | DENN domain containing 10 DENN domain-containing protein 10 (Protein FAM45A) |
Synonyms | FAM45A |
Description | FUNCTION: Guanine nucleotide exchange factor (GEF) regulating homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion, possibly through activating Rab proteins such as RAB27A and RAB27B. Seems to promote the exchange of GDP to GTP, converting inactive GDP-bound RAB27A and RAB27B into their active GTP-bound form. . |
Accessions | Q8TCE6 ENST00000361432.3 [Q8TCE6-1] A0A3B3IRE4 ENST00000648560.1 ENST00000472379.2 A0A3B3IUD3 |