Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 19 studies | 46% ± 19% | |
oligodendrocyte precursor cell | 14 studies | 34% ± 12% | |
ciliated cell | 12 studies | 27% ± 11% | |
glutamatergic neuron | 10 studies | 44% ± 22% | |
epithelial cell of proximal tubule | 8 studies | 23% ± 6% | |
endothelial cell | 8 studies | 29% ± 14% | |
type I pneumocyte | 8 studies | 33% ± 9% | |
GABAergic neuron | 7 studies | 33% ± 18% | |
neuron | 7 studies | 29% ± 10% | |
type II pneumocyte | 7 studies | 31% ± 10% | |
fibroblast | 7 studies | 24% ± 7% | |
retinal ganglion cell | 6 studies | 55% ± 27% | |
epithelial cell | 6 studies | 39% ± 14% | |
Mueller cell | 6 studies | 28% ± 11% | |
interneuron | 5 studies | 26% ± 7% | |
club cell | 5 studies | 25% ± 8% | |
kidney loop of Henle epithelial cell | 4 studies | 20% ± 3% | |
goblet cell | 4 studies | 27% ± 11% | |
granule cell | 4 studies | 21% ± 6% | |
hepatocyte | 4 studies | 59% ± 21% | |
smooth muscle cell | 4 studies | 20% ± 2% | |
transit amplifying cell | 3 studies | 21% ± 0% | |
ependymal cell | 3 studies | 36% ± 14% | |
intestinal crypt stem cell | 3 studies | 25% ± 7% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 33% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 11296.64 | 2633 / 2642 | 99% | 160.31 | 699 / 705 |
kidney | 100% | 8721.11 | 89 / 89 | 96% | 103.00 | 867 / 901 |
stomach | 97% | 2616.57 | 347 / 359 | 99% | 104.31 | 282 / 286 |
prostate | 95% | 2899.13 | 233 / 245 | 100% | 124.92 | 502 / 502 |
liver | 100% | 5379.23 | 226 / 226 | 92% | 57.82 | 375 / 406 |
intestine | 92% | 2985.94 | 893 / 966 | 99% | 102.58 | 520 / 527 |
pancreas | 95% | 2120.43 | 313 / 328 | 95% | 63.56 | 169 / 178 |
thymus | 95% | 2465.59 | 620 / 653 | 87% | 83.64 | 525 / 605 |
breast | 81% | 1455.11 | 372 / 459 | 94% | 59.95 | 1056 / 1118 |
lung | 97% | 3196.26 | 562 / 578 | 76% | 57.84 | 873 / 1155 |
bladder | 95% | 2654.29 | 20 / 21 | 74% | 47.22 | 371 / 504 |
adrenal gland | 99% | 4420.59 | 256 / 258 | 67% | 25.28 | 153 / 230 |
uterus | 73% | 1727.93 | 124 / 170 | 54% | 30.50 | 249 / 459 |
esophagus | 60% | 1174.63 | 862 / 1445 | 62% | 54.86 | 114 / 183 |
ovary | 19% | 311.26 | 35 / 180 | 88% | 36.15 | 378 / 430 |
blood vessel | 96% | 2878.48 | 1281 / 1335 | 0% | 0 | 0 / 0 |
adipose | 76% | 1382.23 | 910 / 1204 | 0% | 0 | 0 / 0 |
muscle | 71% | 1889.12 | 571 / 803 | 0% | 0 | 0 / 0 |
skin | 57% | 3967.64 | 1025 / 1809 | 14% | 4.58 | 65 / 472 |
spleen | 56% | 1027.33 | 135 / 241 | 0% | 0 | 0 / 0 |
heart | 28% | 566.52 | 241 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 16% | 5.56 | 7 / 45 |
lymph node | 0% | 0 | 0 / 0 | 7% | 1.64 | 2 / 29 |
eye | 0% | 0 | 0 / 0 | 3% | 0.89 | 2 / 80 |
peripheral blood | 0% | 4.35 | 3 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0000052 | Biological process | citrulline metabolic process |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0003073 | Biological process | regulation of systemic arterial blood pressure |
GO_0046209 | Biological process | nitric oxide metabolic process |
GO_1900038 | Biological process | negative regulation of cellular response to hypoxia |
GO_0007263 | Biological process | nitric oxide mediated signal transduction |
GO_0045429 | Biological process | positive regulation of nitric oxide biosynthetic process |
GO_0045766 | Biological process | positive regulation of angiogenesis |
GO_0006525 | Biological process | arginine metabolic process |
GO_0006527 | Biological process | arginine catabolic process |
GO_0043116 | Biological process | negative regulation of vascular permeability |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005829 | Cellular component | cytosol |
GO_0016597 | Molecular function | amino acid binding |
GO_0016403 | Molecular function | dimethylargininase activity |
GO_0003824 | Molecular function | catalytic activity |
GO_0046872 | Molecular function | metal ion binding |
Gene name | DDAH1 |
Protein name | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC 3.5.3.18) (DDAHI) (Dimethylargininase-1) Dimethylarginine dimethylaminohydrolase 1, isoform CRA_b (Epididymis secretory protein Li 16) (cDNA, FLJ92778, Homo sapiens dimethylarginine dimethylaminohydrolase 1 (DDAH1), mRNA) Dimethylarginine dimethylaminohydrolase 1 |
Synonyms | hCG_2040048 HEL-S-16 DDAH |
Description | FUNCTION: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. . |
Accessions | B2R644 ENST00000284031.13 [O94760-1] O94760 ENST00000426972.8 [O94760-2] ENST00000633113.1 B4DYP1 |