DCUN1D2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2000434Biological processregulation of protein neddylation
GO_2000436Biological processpositive regulation of protein neddylation
GO_0045116Biological processprotein neddylation
GO_0000151Cellular componentubiquitin ligase complex
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0031624Molecular functionubiquitin conjugating enzyme binding
GO_0097602Molecular functioncullin family protein binding
GO_0005515Molecular functionprotein binding
GO_0032182Molecular functionubiquitin-like protein binding

IV. Literature review

[source]
Gene nameDCUN1D2
Protein nameDCN1-like protein 2 (DCNL2) (DCUN1 domain-containing protein 2) (Defective in cullin neddylation protein 1-like protein 2)
DCN1-like protein (Defective in cullin neddylation protein 1-like protein)
Defective in cullin neddylation 1 domain containing 2
Alternative protein DCUN1D2
SynonymsC13orf17
DCUN1L2
DescriptionFUNCTION: Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and plays an essential role in the regulation of SCF (SKP1-CUL1-F-box protein)-type complexes activity. .

AccessionsQ6PH85
ENST00000478244.6 [Q6PH85-1]
C9J2J1
ENST00000465710.1
ENST00000332592.7
L8E9L0
C9J2J3
ENST00000375403.6 [Q6PH85-2]
ENST00000439909.2
A0A0C4DFQ9
H7C216
ENST00000438545.6
C9JRE2
ENST00000465938.5
C9JAV2
ENST00000496873.1