CTPS2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006220Biological processpyrimidine nucleotide metabolic process
GO_0006541Biological processglutamine metabolic process
GO_0019856Biological processpyrimidine nucleobase biosynthetic process
GO_0006241Biological processCTP biosynthetic process
GO_0044210Biological process'de novo' CTP biosynthetic process
GO_0097268Cellular componentcytoophidium
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0003883Molecular functionCTP synthase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameCTPS2
Protein nameCTP synthase 2 (EC 6.3.4.2) (CTP synthetase 2) (UTP--ammonia ligase 2)
CTP synthase (glutamine hydrolyzing) (EC 6.3.4.2)
Synonyms
DescriptionFUNCTION: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. .

AccessionsENST00000359276.9
Q9NRF8
ENST00000443824.5
H0Y5S6
ENST00000455276.1
ENST00000380241.7