Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 16 studies | 25% ± 10% | |
fibroblast | 14 studies | 24% ± 7% | |
pericyte | 11 studies | 20% ± 4% | |
classical monocyte | 7 studies | 25% ± 9% | |
capillary endothelial cell | 7 studies | 18% ± 4% | |
epithelial cell | 7 studies | 32% ± 12% | |
macrophage | 6 studies | 19% ± 2% | |
abnormal cell | 5 studies | 25% ± 8% | |
connective tissue cell | 5 studies | 24% ± 6% | |
myofibroblast cell | 5 studies | 21% ± 4% | |
type I pneumocyte | 5 studies | 22% ± 6% | |
basal cell | 5 studies | 25% ± 8% | |
astrocyte | 5 studies | 26% ± 9% | |
squamous epithelial cell | 4 studies | 31% ± 22% | |
non-classical monocyte | 4 studies | 30% ± 14% | |
endothelial cell of artery | 4 studies | 19% ± 5% | |
smooth muscle cell | 4 studies | 22% ± 4% | |
ciliated cell | 4 studies | 26% ± 9% | |
endothelial cell of vascular tree | 4 studies | 18% ± 2% | |
goblet cell | 4 studies | 19% ± 4% | |
oligodendrocyte | 4 studies | 22% ± 6% | |
type B pancreatic cell | 3 studies | 34% ± 17% | |
conventional dendritic cell | 3 studies | 23% ± 6% | |
hematopoietic precursor cell | 3 studies | 23% ± 9% | |
glomerular endothelial cell | 3 studies | 19% ± 2% | |
myeloid cell | 3 studies | 24% ± 4% | |
pro-B cell | 3 studies | 21% ± 1% | |
type II pneumocyte | 3 studies | 24% ± 11% | |
glutamatergic neuron | 3 studies | 29% ± 10% | |
oligodendrocyte precursor cell | 3 studies | 34% ± 6% | |
vein endothelial cell | 3 studies | 19% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 18956.85 | 459 / 459 | 100% | 164.61 | 1118 / 1118 |
esophagus | 100% | 18847.78 | 1445 / 1445 | 100% | 149.55 | 183 / 183 |
lung | 100% | 22285.19 | 578 / 578 | 100% | 164.62 | 1155 / 1155 |
stomach | 100% | 15721.40 | 359 / 359 | 100% | 144.85 | 286 / 286 |
intestine | 100% | 20867.93 | 966 / 966 | 100% | 137.02 | 526 / 527 |
ovary | 100% | 21555.88 | 180 / 180 | 100% | 192.68 | 429 / 430 |
prostate | 100% | 17025.09 | 245 / 245 | 100% | 118.29 | 500 / 502 |
brain | 99% | 8931.22 | 2627 / 2642 | 100% | 153.03 | 704 / 705 |
thymus | 100% | 16729.40 | 653 / 653 | 99% | 125.68 | 599 / 605 |
skin | 100% | 18871.79 | 1809 / 1809 | 99% | 157.26 | 467 / 472 |
uterus | 100% | 22498.14 | 170 / 170 | 99% | 129.03 | 454 / 459 |
pancreas | 100% | 12653.57 | 328 / 328 | 99% | 137.87 | 176 / 178 |
kidney | 100% | 12863.10 | 89 / 89 | 98% | 131.65 | 886 / 901 |
bladder | 100% | 18921.10 | 21 / 21 | 97% | 106.09 | 491 / 504 |
adrenal gland | 100% | 17084.08 | 258 / 258 | 93% | 73.28 | 213 / 230 |
liver | 98% | 6801.11 | 222 / 226 | 94% | 68.78 | 381 / 406 |
adipose | 100% | 18891.93 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 118.23 | 80 / 80 |
spleen | 100% | 15703.15 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 145.12 | 45 / 45 |
blood vessel | 100% | 20281.33 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 9482.79 | 859 / 861 | 0% | 0 | 0 / 0 |
muscle | 99% | 10361.96 | 795 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 111.97 | 28 / 29 |
peripheral blood | 95% | 10046.36 | 886 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_2000134 | Biological process | negative regulation of G1/S transition of mitotic cell cycle |
GO_0001933 | Biological process | negative regulation of protein phosphorylation |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0008420 | Molecular function | RNA polymerase II CTD heptapeptide repeat phosphatase activity |
GO_0005515 | Molecular function | protein binding |
GO_0017018 | Molecular function | myosin phosphatase activity |
GO_0046872 | Molecular function | metal ion binding |
Gene name | CTDSP2 |
Protein name | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2) CTD small phosphatase 2 |
Synonyms | OS4 NIF2 SCP2 |
Description | FUNCTION: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. . |
Accessions | F8W184 F8VYL0 H0YI29 O14595 ENST00000551594.1 H0YI12 ENST00000549039.5 ENST00000547701.5 ENST00000548823.1 ENST00000398073.7 ENST00000550144.1 F8W1I1 |