Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 20 studies | 32% ± 15% | |
endothelial cell of lymphatic vessel | 15 studies | 37% ± 18% | |
oligodendrocyte precursor cell | 15 studies | 57% ± 18% | |
astrocyte | 15 studies | 63% ± 23% | |
microglial cell | 13 studies | 56% ± 19% | |
glutamatergic neuron | 10 studies | 43% ± 25% | |
fibroblast | 10 studies | 26% ± 5% | |
macrophage | 9 studies | 39% ± 19% | |
GABAergic neuron | 8 studies | 34% ± 11% | |
endothelial cell of artery | 7 studies | 22% ± 9% | |
CD4-positive, alpha-beta T cell | 5 studies | 23% ± 4% | |
retina horizontal cell | 5 studies | 30% ± 13% | |
B cell | 5 studies | 28% ± 9% | |
cardiac muscle cell | 5 studies | 46% ± 11% | |
neuron | 4 studies | 24% ± 2% | |
mesothelial cell | 4 studies | 39% ± 16% | |
vein endothelial cell | 4 studies | 38% ± 29% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 24% ± 6% | |
GABAergic interneuron | 3 studies | 24% ± 2% | |
myeloid cell | 3 studies | 39% ± 3% | |
endothelial cell of vascular tree | 3 studies | 43% ± 17% | |
ependymal cell | 3 studies | 40% ± 22% | |
capillary endothelial cell | 3 studies | 26% ± 4% | |
chondrocyte | 3 studies | 53% ± 17% | |
smooth muscle cell | 3 studies | 19% ± 2% | |
lymphocyte | 3 studies | 22% ± 4% | |
plasma cell | 3 studies | 31% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 4118.93 | 245 / 245 | 100% | 81.71 | 501 / 502 |
thymus | 100% | 7590.63 | 653 / 653 | 96% | 30.36 | 578 / 605 |
brain | 85% | 2146.92 | 2233 / 2642 | 99% | 26.58 | 699 / 705 |
lung | 99% | 2008.67 | 574 / 578 | 80% | 8.66 | 926 / 1155 |
breast | 99% | 1797.60 | 454 / 459 | 75% | 7.89 | 843 / 1118 |
esophagus | 97% | 1705.35 | 1401 / 1445 | 77% | 8.78 | 141 / 183 |
pancreas | 81% | 741.55 | 267 / 328 | 90% | 11.29 | 161 / 178 |
adrenal gland | 98% | 2009.06 | 254 / 258 | 70% | 14.16 | 162 / 230 |
kidney | 96% | 1311.38 | 85 / 89 | 68% | 13.41 | 617 / 901 |
stomach | 96% | 1121.29 | 346 / 359 | 67% | 7.07 | 193 / 286 |
skin | 71% | 813.89 | 1293 / 1809 | 89% | 38.59 | 420 / 472 |
uterus | 97% | 1597.02 | 165 / 170 | 58% | 5.88 | 266 / 459 |
bladder | 100% | 5119.19 | 21 / 21 | 50% | 4.80 | 254 / 504 |
intestine | 81% | 908.19 | 780 / 966 | 56% | 5.51 | 293 / 527 |
ovary | 99% | 3657.03 | 179 / 180 | 11% | 0.71 | 47 / 430 |
adipose | 100% | 3447.54 | 1202 / 1204 | 0% | 0 | 0 / 0 |
heart | 98% | 3291.92 | 842 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 97% | 2285.26 | 1299 / 1335 | 0% | 0 | 0 / 0 |
spleen | 95% | 1753.76 | 230 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 67% | 1527.48 | 624 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 67% | 5.14 | 30 / 45 |
liver | 12% | 71.50 | 26 / 226 | 26% | 6.37 | 104 / 406 |
muscle | 24% | 172.10 | 194 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 24% | 1.55 | 7 / 29 |
eye | 0% | 0 | 0 / 0 | 15% | 2.09 | 12 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050650 | Biological process | chondroitin sulfate proteoglycan biosynthetic process |
GO_0030166 | Biological process | proteoglycan biosynthetic process |
GO_0015014 | Biological process | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process |
GO_0030206 | Biological process | chondroitin sulfate biosynthetic process |
GO_0050653 | Biological process | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process |
GO_0050651 | Biological process | dermatan sulfate proteoglycan biosynthetic process |
GO_0030210 | Biological process | heparin biosynthetic process |
GO_0046398 | Biological process | UDP-glucuronate metabolic process |
GO_0030198 | Biological process | extracellular matrix organization |
GO_0001958 | Biological process | endochondral ossification |
GO_0019276 | Biological process | UDP-N-acetylgalactosamine metabolic process |
GO_0051216 | Biological process | cartilage development |
GO_0000139 | Cellular component | Golgi membrane |
GO_0032580 | Cellular component | Golgi cisterna membrane |
GO_0008376 | Molecular function | acetylgalactosaminyltransferase activity |
GO_0015020 | Molecular function | glucuronosyltransferase activity |
GO_0047237 | Molecular function | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity |
GO_0008955 | Molecular function | peptidoglycan glycosyltransferase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0047238 | Molecular function | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity |
Gene name | CSGALNACT1 |
Protein name | Hexosyltransferase (EC 2.4.1.-) Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CsGalNAcT-1) (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1) (Beta4GalNAcT-1) Chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
Synonyms | CHGN UNQ656/PRO1287 GALNACT1 |
Description | FUNCTION: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage formation and subsequent endochondral ossification . Moreover, is involved in the metabolism of aggrecan (By similarity). . |
Accessions | ENST00000695898.1 [Q8TDX6-1] ENST00000695899.1 [Q8TDX6-3] ENST00000695895.1 [Q8TDX6-1] E5RJB6 A0A8Q3WKU9 ENST00000523262.5 ENST00000519222.5 [Q8TDX6-3] ENST00000454498.6 [Q8TDX6-1] E5RGK2 ENST00000695897.1 [Q8TDX6-1] ENST00000695893.1 [Q8TDX6-1] ENST00000695900.1 E5RK93 ENST00000332246.10 [Q8TDX6-1] ENST00000695892.1 [Q8TDX6-1] ENST00000692225.2 [Q8TDX6-1] ENST00000517494.1 ENST00000695896.1 [Q8TDX6-1] ENST00000522854.5 [Q8TDX6-1] Q8TDX6 ENST00000520003.5 ENST00000524213.5 E5RGB2 ENST00000397998.7 [Q8TDX6-3] ENST00000695894.1 [Q8TDX6-1] |