I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 5 studies | 41% ± 10% | |
| retinal ganglion cell | 3 studies | 57% ± 23% | |
| smooth muscle cell | 3 studies | 19% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 5 studies | 41% ± 10% | |
| retinal ganglion cell | 3 studies | 57% ± 23% | |
| smooth muscle cell | 3 studies | 19% ± 1% |
Insufficient scRNA-seq data for expression of CSDC2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 89% | 3834.35 | 2345 / 2642 | 96% | 84.55 | 676 / 705 |
| adrenal gland | 100% | 17802.30 | 258 / 258 | 76% | 47.02 | 175 / 230 |
| prostate | 82% | 3509.78 | 200 / 245 | 85% | 8.73 | 426 / 502 |
| ovary | 100% | 16797.98 | 180 / 180 | 53% | 5.23 | 228 / 430 |
| kidney | 93% | 4164.29 | 83 / 89 | 58% | 14.63 | 525 / 901 |
| pancreas | 75% | 3582.21 | 247 / 328 | 66% | 5.17 | 117 / 178 |
| uterus | 98% | 10223.19 | 167 / 170 | 33% | 8.18 | 152 / 459 |
| bladder | 86% | 3605.86 | 18 / 21 | 28% | 2.74 | 143 / 504 |
| lung | 63% | 1200.83 | 362 / 578 | 43% | 2.97 | 500 / 1155 |
| blood vessel | 99% | 10611.19 | 1322 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 21231.10 | 848 / 861 | 0% | 0 | 0 / 0 |
| intestine | 39% | 955.08 | 380 / 966 | 20% | 1.34 | 106 / 527 |
| esophagus | 20% | 347.53 | 288 / 1445 | 22% | 1.16 | 40 / 183 |
| breast | 6% | 117.86 | 29 / 459 | 35% | 2.31 | 391 / 1118 |
| stomach | 8% | 138.82 | 30 / 359 | 25% | 1.47 | 71 / 286 |
| adipose | 23% | 435.95 | 271 / 1204 | 0% | 0 | 0 / 0 |
| skin | 2% | 42.79 | 33 / 1809 | 5% | 0.59 | 24 / 472 |
| thymus | 4% | 75.18 | 23 / 653 | 3% | 0.17 | 17 / 605 |
| eye | 0% | 0 | 0 / 0 | 6% | 0.67 | 5 / 80 |
| liver | 2% | 26.54 | 4 / 226 | 3% | 0.28 | 12 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.15 | 1 / 45 |
| muscle | 1% | 21.34 | 11 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006397 | Biological process | mRNA processing |
| GO_0043488 | Biological process | regulation of mRNA stability |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0003730 | Molecular function | mRNA 3'-UTR binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | CSDC2 |
| Protein name | Cold shock domain containing C2 Cold shock domain-containing protein C2 (RNA-binding protein PIPPin) |
| Synonyms | PIPPIN |
| Description | FUNCTION: RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity). . |
| Accessions | Q9Y534 H7C4E7 ENST00000306149.12 ENST00000460790.1 |
